Successful treatment of aggressive AA amyloidosis with tocilizumab in a patient with polymyalgia rheumatica

被引:0
|
作者
Atas, Nuh [1 ]
Caliskan, Ali Riza [2 ]
Akatli, Aysenur [3 ]
机构
[1] Adiyaman Educ & Res Hosp, Dept Internal Med, Div Rheumatol, TR-2230 Adiyaman, Turkiye
[2] Adiyaman Educ & Res Hosp, Dept Internal Med, Div Gastroenterol, Adiyaman, Turkiye
[3] Inonu Univ, Fac Med, Dept Pathol, Malatya, Turkiye
关键词
Polymyalgia rheumatica; AA amyloidosis; tocilizumab; IL-6; proteinuria; SECONDARY;
D O I
10.1093/mrcr/rxae050
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Polymyalgia rheumatic (PMR) associated amyloidosis is an extremely rare condition that can be rapidly progressive with high morbidity and mortality and management is challenging. Tocilizumab is a monoclonal anti-IL-6 receptor antibody, which is in the therapeutic arsenal of PMR. The efficiency of tocilizumab in improvement of PMR activity score and decreasing steroid dose is well-established, while efficiency in PMR-associated amyloidosis has not been published. Herein, we reported a PMR patient with amyloid A amyloidosis who was treated effectively with tocilizumab.
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页数:4
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