Synthesis of Novel Sulfonamide Derivatives Featuring 1-(Methylsulfonyl)-4-(2,3,4-Trimethoxybenzyl)Piperazine Core Structures

被引：0

作者：

Ivanov, Iliyan ^{[1
]}

Manolov, Stanimir ^{[1
]}

Bojilov, Dimitar ^{[1
]}

Dimitrova, Diyana ^{[1
]}

Nedialkov, Paraskev ^{[2
]}

机构：

[1] Paisij Hilendarski Univ Plovdiv, Fac Chem, Dept Organ Chem, 24 Tsar Assen Str, Plovdiv 4000, Bulgaria

[2] Med Univ Sofia, Fac Pharm, Dept Pharmacognosy, 2 Dunav Str, Sofia 1000, Bulgaria

来源：

MOLBANK | 2024年 / 2024卷 / 03期

关键词：

trimetazidine; 1-(2,3,4-trimethoxybenzyl)piperazine; sulfonamides; methanesulfonyl chloride; benzenesulfonyl chloride; phenylmethanesulfonyl chloride; angina pectoris; doping; TRIMETAZIDINE; DRUGS;

D O I：

10.3390/M1879

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein we report the synthesis of three novel sulfonamide derivatives of trimetazidine-medication primarily used to treat angina pectoris. The new compounds have been fully characterized with their melting point, 1H- and 13C-NMR, UV, and mass spectrometry. The collected data confirm the successful synthesis and structural integrity of the new molecules.

引用

页数：5

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