Follow-up of cognitive impairment and inflammatory profile in individuals with mild COVID-19

被引：3
|
作者：
Souza-Silva, Nathalia Gualberto [1 ]
Rosa, Daniela Valadao [1 ]
de Paula, Jonas Jardim [1 ,3 ]
Coimbra, Roney Santos [4 ]
Miranda, Debora Marques [1 ,2 ]
Romano-Silva, Marco Aurelio [1 ,3 ]
机构：
[1] Univ Fed Minas Gerais UFMG, Ctr Tecnol Med Mol CTMM, Ave Alfredo Balena 190, Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais UFMG, Dept Pediat, Fac Med, Belo Horizonte, MG, Brazil
[3] Univ Fed Minas Gerais UFMG, Dept Psiquiatria, Fac Med, Ave Alfredo Balena 190,Sala 114, BR-30130100 Belo Horizonte, MG, Brazil
[4] Fiocruz MS, Inst Rene Rachou, Neurogen Imunopatol, Belo Horizonte, MG, Brazil
来源：
JOURNAL OF NEUROIMMUNOLOGY | 2024年 / 389卷
关键词：
Post-acute COVID-19 syndrome; Neuroinflammation; Cytokine; Cognitive symptoms; Visuospatial processing; NEUROINFLAMMATION;
D O I：
10.1016/j.jneuroim.2024.578327
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Individuals who experience mild COVID-19 can suffer from long-lasting cognitive symptoms. Notably, 26% of these individuals experience difficulties with visuospatial abilities six months after infection. However, among those who initially exhibited visuoconstructive impairments, 66% showed improvement or complete reversal over time. Additionally, changes in cytokine levels, particularly CCL11, HGF, and CXCL10, were observed. These results suggest a potential link between ongoing cognitive issues and elevated levels of pro-inflammatory cytokines, which merits further investigation.
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收藏
页数：6
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