Asiatic Acid, Quercetin, and Kaempferol From Centella asiatica as Potential Inhibitors of Alpha-1-Antichymotrypsin in Alzheimer's Disease

被引:0
|
作者
Chatterjee, Jhinuk [1 ]
Atmuri, Apoorva [1 ]
Raichur, Eshaana Janardhan [1 ]
Anil, Gouri [1 ]
机构
[1] PES Univ, Dept Biotechnol, Bangalore, India
关键词
alpha-1-antichymotrypsin; asiatic acid; quercetin; kaempferol; molecular docking;
D O I
10.1177/1934578X241264637
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Selected compounds from Centella asiatica with proven neuroprotective potential and analyzed strong binding affinity with molecular docking can be considered as potential inhibitors for alpha-1-antichymotrypsin in Alzheimer's disease.
引用
收藏
页数:2
相关论文
共 50 条
  • [21] alpha(1)-Antichymotrypsin gene polymorphism and risk for Alzheimer's disease
    Muramatsu, T
    Matsushita, S
    Arai, H
    Sasaki, H
    Higuchi, S
    JOURNAL OF NEURAL TRANSMISSION, 1996, 103 (10) : 1205 - 1210
  • [22] Apolipoprotein E and alpha(1)-antichymotrypsin polymorphism in Alzheimer's disease
    Nacmias, B
    Tedde, A
    Latorraca, S
    Piacentini, S
    Bracco, L
    Amaducci, L
    Guarnieri, BM
    Petruzzi, C
    Ortenzi, L
    Sorbi, S
    ANNALS OF NEUROLOGY, 1996, 40 (04) : 678 - 680
  • [23] No effect of the alpha 1-antichymotrypsin A allele in Alzheimer's disease
    Didierjean, O
    Martinez, M
    Campion, D
    Hannequin, D
    Dubois, B
    Martin, C
    Puel, M
    Anterion, CT
    Pasquier, F
    Moreau, O
    Babron, MC
    Penet, C
    Agid, Y
    ClergetDarpoux, F
    Frebourg, T
    Brice, A
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1997, 63 (01): : 103 - 105
  • [24] Apolipoprotein E and alpha(1)-antichymotrypsin polymorphism in Alzheimer's disease
    Nacmias, B
    Tedde, A
    Latorraca, S
    Forleo, P
    Piacentini, S
    Sorbi, S
    Amaducci, L
    ANNALS OF NEUROLOGY, 1996, 40 (03) : M54 - M54
  • [25] Alpha-1-antichymotrypsin (ACT or SERPINA3) polymorphism may affect age-at-onset and disease duration of Alzheimer's disease
    Kamboh, M. Ilyas
    Minster, Ryan L.
    Kenney, Margaret
    Ozturk, Ayla
    Desai, Purnima P.
    Kammerer, Candace M.
    DeKosky, Steven T.
    NEUROBIOLOGY OF AGING, 2006, 27 (10) : 1435 - 1439
  • [26] Is there an association of regulatory region polymorphism in the alpha-1-antichymotrypsin gene with sporadic Alzheimer's disease in the northern Han-Chinese population?
    Yu, Guran
    Jia, Jianping
    JOURNAL OF CLINICAL NEUROSCIENCE, 2010, 17 (06) : 766 - 769
  • [27] A Coronary Artery Disease Monitoring Model Built from Clinical Data and Alpha-1-Antichymotrypsin
    Chang, Chen-Chi
    Tsai, I-Jung
    Shen, Wen-Chi
    Chen, Hung-Yi
    Hsu, Po-Wen
    Lin, Ching-Yu
    DIAGNOSTICS, 2022, 12 (06)
  • [28] Rate of cognitive decline in Alzheimer's disease is not affected by the alpha-1-antichymotrypsin A allele or the CYP2D6 B mutant
    Murphy, GM
    Yang, L
    Yesavage, J
    Tinklenberg, JR
    NEUROSCIENCE LETTERS, 1996, 217 (2-3) : 200 - 202
  • [29] alpha 1-antichymotrypsin polymorphism in Japanese cases of Alzheimer's disease
    Yoshizawa, T
    YamakawaKobayashi, K
    Hamaguchi, H
    Shoji, S
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 1997, 152 (02) : 136 - 139
  • [30] Regional distribution of alpha 1-antichymotrypsin immunoreactivity in Alzheimer's disease
    DeKosky, ST
    Styren, SD
    Kamboh, I
    NEUROLOGY, 1997, 48 (03) : 2038 - 2038