Higher-order asymptotic refinements in a multivariate regression model with general parameterization

This paper derives a general Bartlett correction formula to improve the inference based on the likelihood ratio test in a multivariate model under a quite general parameterization, where the mean vector and the variance-covariance matrix can share the same vector of parameters. This approach includes a number of models as special cases such as non-linear regression models, errors-in-variables models, mixed-effects models with non-linear fixed effects, and mixtures of the previous models. We also employ the Skovgaard adjustment to the likelihood ratio statistic in this class of multivariate models and derive a general expression of the correction factor based on Skovgaard approach. Monte Carlo simulation experiments are carried out to verify the performance of the improved tests, and the numerical results confirm that the modified tests are more reliable than the usual likelihood ratio test. Applications to real data are also presented for illustrative purposes.