Isoxazole group directed Rh(III)-catalyzed alkynylation using TIPS-EBX

被引：0
|
作者：
Das, Sukanya [1 ]
Datta, Tanmoy [2 ]
Sk, Md. Abbasuddin [1 ]
Roy, Brindaban [2 ]
Nandi, Raj K. [1 ]
机构：
[1] Jadavpur Univ, Dept Chem, 188 Raja Subodh Chandra Mallick Rd, Kolkata 700032, West Bengal, India
[2] Kalyani Univ, Dept Chem, Block C, Kalyani 741235, West Bengal, India
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 34期
关键词：
C-H ALKYNYLATION; ARENES; BONDS; ETHYNYLATION; HETEROCYCLES; ALKYNES; RH(III);
D O I：
10.1039/d4ob00797b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly effective isoxazole directed ortho C-H alkynylation has been developed. Rhodium(iii) catalyzed direct di-(and/or mono) alkynylation using a hypervalent iodine reagent (TIPS-EBX) is reported. The reaction proceeds with a wide substrate scope under benign conditions. Preliminary mechanistic studies support this chelation assisted C-H alkynylation.
引用
收藏
页码：6922 / 6927
页数：7
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