cervical dystonia;
physiotherapy;
pain;
botulinum neurotoxin;
quality of life;
DEEP BRAIN-STIMULATION;
BOTULINUM TOXIN;
D O I:
暂无
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Background: Cervical dystonia (CD) is the most common form of focal dystonia in adults. Studies show that physiotherapy (PT) in combination with BoNT has an effect on pain in cervical dystonia. We intended to test this hypothesis in a real-world setting to answer the question of whether pain is a good target symptom for prescribing PT. We also aimed to assess which form of PT is most appropriate for the treatment of pain. Methods: Study design: cross-sectional survey-based study of 91 patients with a confirmed diagnosis of cervical dystonia. The survey consisted of a questionnaire on type, frequency and content of physiotherapy, an assessment of quality of life with the Craniocervical Dystonia Questionnaire 24 (CDQ 24) and subjective pain scores. Results: 53.8% of patients received physiotherapy, mostly a mixture of exercises to either correct the abnormal posture or to reduce the muscle tone. Additional therapies included stress-reducing exercises (14.3%), psychotherapy (9.9%) and EMG biofeedback (2.2%). Patients who received PT showed a non-significant tendency towards higher pain scores. The severity of dystonia-associated pain was significantly associated with the patients' quality of life (F (1,54) = 22.9, adjusted R-2 = 0.286, p < 0.001). Discussion: Pain is a frequent problem in patients with CD and severely affects quality of life. Physiotherapy could therefore be a valuable treatment option for patients with CD and pain.
机构:
Univ Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Vu, Jeanne P.
Lee, Ha Yeon
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机构:
Univ Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Lee, Ha Yeon
Chen, Qiyu
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机构:
Univ Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Chen, Qiyu
Cisneros, Elizabeth
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h-index: 0
机构:
Univ Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Cisneros, Elizabeth
Barbano, Richard L.
论文数: 0引用数: 0
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机构:
Univ Rochester, Dept Neurol, Rochester, NY USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Barbano, Richard L.
Goetz, Christopher G.
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h-index: 0
机构:
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Goetz, Christopher G.
Jankovic, Joseph
论文数: 0引用数: 0
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机构:
Baylor Coll Med, Dept Neurol, Parkinsons Dis Ctr, Houston, TX 77030 USA
Baylor Coll Med, Movement Disorders Clin, Houston, TX 77030 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Jankovic, Joseph
Jinnah, Hyder A.
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Neurol, Atlanta, GA 30322 USA
Emory Univ, Dept Human Genet, Atlanta, GA 30322 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Jinnah, Hyder A.
Perlmutter, Joel S.
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机构:
Washington Univ, Sch Med, Dept Neurol, St Louis, MO USA
Washington Univ, Sch Med, Dept Radiol, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Neurosci, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Phys Therapy, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Occupat Therapy, St Louis, MO 63110 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Perlmutter, Joel S.
Berman, Brian D.
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机构:
Virginia Commonwealth Univ, Dept Neurol, Richmond, VA USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Berman, Brian D.
Appelbaum, Mark I.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Psychol, La Jolla, CA 92093 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Appelbaum, Mark I.
Stebbins, Glenn T.
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h-index: 0
机构:
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Stebbins, Glenn T.
Comella, Cynthia L.
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机构:
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Comella, Cynthia L.
Peterson, David A.
论文数: 0引用数: 0
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机构:
Univ Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA
Salk Inst Biol Studies, Computat Neurobiol Lab, 10010 N Torrey Pines Rd, San Diego, CA 92037 USAUniv Calif San Diego, Inst Neural Computat, San Diego, CA 92093 USA