DNA-Based Molecular Machines: Controlling Mechanisms and Biosensing Applications

被引：1

作者：

Ma, Chunran ^{[1
]}

Li, Shiquan ^{[1
]}

Zeng, Yuqi ^{[1
]}

Lyu, Yifan ^{[1
,2
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, Aptamer Engn Ctr Hunan Prov, Mol Sci & Biomed Lab MBL,State Key Lab Chemo Biose, Changsha 410082, Peoples R China

[2] Furong Lab, Changsha 410082, Peoples R China

来源：

BIOSENSORS-BASEL | 2024年 / 14卷 / 05期

关键词：

molecular machines; DNA nanotechnology; controlling mechanism; biosensing; multiplex detection; real-time monitoring; ANTIGEN-DETECTION; PH CHANGES; WALKING; WALKER; DRIVEN; MOTOR; NANOMACHINE; ACTIVATION; TRANSPORT; TWEEZERS;

D O I：

10.3390/bios14050236

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The rise of DNA nanotechnology has driven the development of DNA-based molecular machines, which are capable of performing specific operations and tasks at the nanoscale. Benefitting from the programmability of DNA molecules and the predictability of DNA hybridization and strand displacement, DNA-based molecular machines can be designed with various structures and dynamic behaviors and have been implemented for wide applications in the field of biosensing due to their unique advantages. This review summarizes the reported controlling mechanisms of DNA-based molecular machines and introduces biosensing applications of DNA-based molecular machines in amplified detection, multiplex detection, real-time monitoring, spatial recognition detection, and single-molecule detection of biomarkers. The challenges and future directions of DNA-based molecular machines in biosensing are also discussed.

引用

页数：24

共 50 条

[41] Microfluidics-Based Lab-on-Chip Systems in DNA-Based Biosensing: An Overview
Dutse, Sabo Wada
Yusof, Nor Azah
SENSORS, 2011, 11 (06): : 5754 - 5768
[42] Label-free DNA-based biosensing using luminescent metal complexes
Ma, Dik-Lung
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2014, 19 : S754 - S755
[43] Recent advances on the DNA-based electrochemical biosensing of cancer biomarkers: Analytical approach
Sadighbayan, Deniz
Sadighbayan, Khosrow
Khosroushahi, Ahmad Yari
Hasanzadeh, Mohammad
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2019, 119
[44] Operation kinetics of a DNA-based molecular switch
Simmel, FC
Yurke, B
Sanyal, RJ
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2002, 2 (3-4) : 383 - 390
[45] The cell as the smallest DNA-based molecular computer
Ji, S
BIOSYSTEMS, 1999, 52 (1-3) : 123 - 133
[46] DNA-based molecular lithography for nanoscale fabrication
Brenan, CJH
IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE, 2002, 21 (06): : 164 - 164
[47] A dual input DNA-based molecular switch
Nesterova, Irina V.
Elsiddieg, Siddieg O.
Nesterov, Evgueni E.
MOLECULAR BIOSYSTEMS, 2014, 10 (11) : 2810 - 2814
[48] DNA-Based Molecular Engineering of the Cell Membrane
Li, Xiaodong
Wang, Tiantian
Sun, Yue
Li, Chang
Peng, Tianhuan
Qiu, Liping
MEMBRANES, 2022, 12 (02)
[49] DNA-Based Molecular Computing, Storage, and Communications
Liu, Qiang
Yang, Kun
Xie, Jialin
Sun, Yue
IEEE INTERNET OF THINGS JOURNAL, 2022, 9 (02) : 897 - 915
[50] Construction and applications of DNA-based nanomaterials in cancer therapy
Qi, Hedong
Xu, Yuwei
Hu, Pin
Yao, Chi
Yang, Dayong
CHINESE CHEMICAL LETTERS, 2022, 33 (03) : 1131 - 1140

← 1 2 3 4 5 →