Tislelizumab (TIS) plus chemotherapy (Chemo) vs placebo (PBO) plus chemo as first-line (1L) treatment of advanced gastric or gastroesophageal junction adenocarcinoma (GC/GEJC): Health-related quality of life (HRQoL) outcomes in the RATIONALE-305 study.

被引:0
|
作者
Cruz-Correa, Marcia
Xu, Rui-Hua
Moehler, Markus H.
Oh, Do-Youn
Kato, Ken
Spigel, David R.
Arkenau, Hendrik-Tobias
Tabernero, Josep
Zimina, Anastasia V.
Bai, Yuxian
Shi, Jianhua
Lee, Keun-Wook
Hirano, Hidekazu
Wyrwicz, Lucjan S.
Pazo Cid, Roberto
Xu, Hui
Sheng, Tao
Barnes, Gisoo
机构
[1] Univ Puerto Rico, Sch Med, San Juan, PR 00936 USA
[2] Sun Yat Sen Univ, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China, Canc Ctr, Guangzhou, Peoples R China
[3] Johannes Gutenberg Univ Clin, Dept Internal Med, Mainz, Germany
[4] Seoul Natl Univ Hosp, Dept Internal Med, Div Med Oncol, Seoul, South Korea
[5] Seoul Natl Univ, Canc Res Inst, Coll Med, Seoul, South Korea
[6] Natl Canc Ctr, Tokyo, Japan
[7] Sarah Cannon Res Inst, Tennessee Oncol, Nashville, TN USA
[8] Sarah Cannon Res, London, England
[9] Vall DHebron Univ Hosp & Inst Oncol VHIO, Barcelona, Spain
[10] BHI Omsk Reg Clin Oncol Dispensary, Omsk, Russia
[11] Harbin Med Univ Canc Hosp, Dept Gastrointestinal Oncol, Harbin, Peoples R China
[12] Linyi Canc Hosp, Dept Med Oncol, Linyi, Peoples R China
[13] Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea
[14] Natl Canc Ctr Hosp, Dept Gastrointestinal Med Oncol, Chuo City, Japan
[15] Maria Sklodowska Curie Natl Res Inst Oncol, Warsaw, Poland
[16] Hosp Univ Miguel Servet, Zaragoza, Spain
[17] BeiGene Beijing Co Ltd, Beijing, Peoples R China
[18] BeiGene USA Inc, San Mateo, CA USA
关键词
261-566-148; 613-135-2370-7650-2700; 130-274-2403; 613-302-309; 613-302-312-303; 17; 9; 3; 2; 2424; 1704;
D O I
10.1200/JCO.2024.42.3_suppl.290
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:290 / 290
页数:1
相关论文
共 50 条
  • [41] Longitudinal ctDNA levels and clinical outcomes of first-line (1L) tislelizumab (TIS) plus chemotherapy (chemo) treatment for advanced non-small cell lung cancer (NSCLC) in the RATIONALE-304 and 307 studies
    Lu, Shun
    Wang, Jie
    Sun, Meili
    Zhao, Jun
    Hu, Chunhong
    Wang, Mengzhao
    Zhou, Jianying
    Song, Yong
    Zhou, Qinghua
    Zhang, Jiayuan
    Shi, Yang
    Huang, Ruiqi
    Wu, Xikun
    He, Wanyu
    Qu, Xiaofei
    Zhang, Yun
    Shen, Zhirong
    Yu, Yan
    CANCER RESEARCH, 2023, 83 (08)
  • [42] RATIONALE 307: Tislelizumab (TIS) plus chemotherapy (chemo) vs chemo alone as first-line (1L) treatment for advanced squamous non-small cell lung cancer (sq NSCLC) in patients (pts) who were smokers vs non-smokers
    Yu, X.
    Wang, J.
    Lu, S.
    Zhao, J.
    Yu, Y.
    Hu, C.
    Feng, G.
    Ying, K.
    Zhuang, W.
    Zhou, J.
    Wu, J.
    Leaw, S. J.
    Lin, X.
    Zhang, J.
    ANNALS OF ONCOLOGY, 2021, 32 : S1005 - S1005
  • [43] First-line nivolumab (NIVO) plus chemotherapy (chemo) vs chemo in patients with advanced gastric cancer/gastroesophageal junction cancer/esophageal adenocarcinoma (GC/GEJC/EAC): CheckMate 649 Chinese subgroup analysis 2-year follow-up
    Shen, L.
    Bai, Y.
    Lin, X.
    Li, W.
    Wang, J.
    Zhang, X.
    Pan, H.
    Bai, C.
    Bai, L.
    Cheng, Y.
    Zhang, J.
    Zhong, H.
    Ba, Y.
    Hu, W.
    Xu, R.
    Guo, W.
    Qin, S.
    Yang, N.
    Lu, J.
    Chanaga, C. Amaya
    Soleymani, S.
    Liu, T.
    ANNALS OF ONCOLOGY, 2022, 33 : S279 - S279
  • [44] Cost-effectiveness of tislelizumab plus chemotherapy vs chemotherapy as first-line treatment of PD-L1 positive advanced gastric or gastroesophageal junction adenocarcinoma from a Chinese perspective
    Li, Wei
    Wan, Li
    Zhang, Jiangyan
    EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2024, 18 (06) : 293 - 301
  • [45] Cost-effectiveness analysis of tislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced gastric or gastroesophageal junction adenocarcinoma: perspectives from the United States and China
    Lang, Wenwang
    Ai, Qi
    Zhang, Wenwen
    Jiang, Qinling
    He, Yulong
    Ouyang, Ming
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [46] Health-related quality of life (HRQoL) impact of lenvatinib (len) plus pembrolizumab (pembro) versus len plus placebo (pbo) as first-line (1L) therapy for advanced hepatocellular carcinoma (aHCC): Phase 3 LEAP-002 study.
    Llovet, Josep M.
    Kudo, Masatoshi
    Merle, Philippe
    Meyer, Tim
    Qin, Shukui
    Ikeda, Masafumi
    Xu, Ruocai
    Edeline, Julien
    Ryoo, Baek-Yeol
    Ren, Zhenggang
    Cheng, Ann-Lii
    Galle, Peter R.
    Kaneko, Shuichi
    Kumada, Hiromitsu
    Kamble, Shital
    Norquist, Josephine M.
    Mody, Kalgi
    Dubrovsky, Leonid
    Siegel, Abby B.
    Finn, Richard S.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 : 506 - 506
  • [47] Nivolumab (NIVO) plus ipilimumab (IPI) or NIVO plus chemotherapy (chemo) versus chemo as first-line (1L) treatment for advanced esophageal squamous cell carcinoma (ESCC): First results of the CheckMate 648 study.
    Chau, Ian
    Doki, Yuichiro
    Ajani, Jaffer A.
    Xu, Jianming
    Wyrwicz, Lucjan
    Motoyama, Satoru
    Ogata, Takashi
    Kawakami, Hisato
    Hsu, Chih-Hung
    Adenis, Antoine
    El Hajbi, Farid
    Di Bartolomeo, Maria
    Freitas Melro Braghiroli, Maria Ignez
    Holtved, Eva
    Xynos, Ioannis
    Liu, Xuan
    Lei, Ming
    Kondo, Kaoru
    Kato, Ken
    Kitagawa, Yuko
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (18)
  • [48] Phase (Ph) II study of zanidatamab plus chemotherapy (chemo) in first-line (1L) HER2 expressing gastroesophageal adenocarcinoma (GEA)
    Ku, G.
    Elimova, E.
    Denlinger, C. S.
    Mehta, R.
    Lee, K-W.
    Iqbal, S.
    Kang, Y-K.
    Oh, D-Y.
    Rha, S. Y.
    Kim, Y. H.
    Seol, Y. M.
    Mwatha, T.
    Grim, J.
    Ajani, J. A.
    ANNALS OF ONCOLOGY, 2021, 32 : S1044 - S1045
  • [49] First-line (1L) tislelizumab (TIS) plus chemotherapy (CT) vs placebo (PBO) plus CT in advanced/metastatic esophageal squamous cell carcinoma (ESCC): RATIONALE-306 Japanese subgroup analysis with longer follow-up.
    Kojima, Takashi
    Ogata, Takashi
    Ishihara, Ryu
    Hara, Hiroki
    Sun, Tianmo
    Xu, Sheng
    Kato, Ken
    JOURNAL OF CLINICAL ONCOLOGY, 2025, 43 (4_SUPPL) : 420 - 420
  • [50] AdvanTIG-105: A phase 1b dose-expansion study of ociperlimab (OCI) plus tislelizumab (TIS) with chemotherapy (chemo) in patients (pts) with stage IV gastric/gastroesophageal adenocarcinoma (GC/GEJC)
    Kim, Se Hyun
    Lee, Gyeong-Won
    Shim, Byoung Yong
    Spigel, David R.
    Shiah, Her-Shyong
    Frentzas, Sophia
    Yoon, Harry H.
    Wang, Feng
    Sun, Meili
    Clay, Timothy Dudley
    Zheng, Hao
    Tan, Wei
    Zhou, Ziqi
    Wang, Ruihua
    Ba, Yi
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)