Results of surgical treatment of lymph node metastases in patients with cutaneous squamous cell carcinoma of the head and neck

被引:0
|
作者
Leon, Xavier [1 ,2 ]
Lopez, Susana [3 ]
Perez, Maria [3 ]
Valero, Cristina [1 ]
Holgado, Anna [1 ]
Quer, Miquel [1 ,2 ]
Vega, Carmen [3 ]
机构
[1] Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Serv Otorrinolaringol, Barcelona, Spain
[2] Ctr Invest Biomed Red Bioingn Biomat & Nanomed CIB, Madrid, Spain
[3] Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Serv Cirugia Plast, Barcelona, Spain
来源
ACTA OTORRINOLARINGOLOGICA ESPANOLA | 2024年 / 75卷 / 03期
关键词
Cutaneous squamous cell carcinoma; Head and neck; Lymph node metastases; Parotidectomy; Neck dissection; Extracapsular spread; Prognostic classification; O'Brien; SPREAD; CANCER; PROGNOSIS; OUTCOMES; SURGERY; SYSTEM;
D O I
10.1016/j.otorri.2023.07.007
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Introduction: Out of all cutaneous squamous cell carcinomas originating in the head and neck (HNCSCC), 2%-4% are associated with parotid or cervical lymph node metastasis. The aim of this study is to analyse the prognostic factors of patients with HNCSCC with lymph node involvement treated surgically. Additionally, we aim to compare the prognostic capacity of the classification of these patients according to the 8th edition of the TNM, and an alternative classification proposed by O'Brien et al. Patients and methods: Retrospective review of 65 patients with HNCSCC with lymph node metastasis treated surgically during the period 2000-2020. Results: During the study period we carried out 13 neck dissections and 52 parotidectomies + neck dissection in patients with lymph node metastases from a HNCSCC. The great majority of patients (89.2%) received post -operative radiotherapy. The 5 year disease -specific survival was 69.9%, and the overall survival it was 42.8%. The classification proposed by O'Brien et al., based on the parotid or cervical location of the lymph node metastases, and the size and number of the metastatic lymph nodes, had a better prognostic capacity than the TNM classification. Conclusions: The surgical treatment of lymph node metastases in patients with HNCSCC achieved a high disease control. The classification based on the location, size and number of lymph node metastases proposed by O'Brien et al. had better prognostic capacity than the TNM classification. (c) 2023 Sociedad Espa & ntilde;ola de Otorrinolaringolog & iacute;a y Cirug & iacute;a de Cabeza y Cuello. Published by Elsevier Espa & ntilde;a, S.L.U. All rights reserved.
引用
收藏
页码:169 / 176
页数:8
相关论文
共 50 条
  • [21] Outcomes of Sentinel Lymph Node Biopsy for Primary Cutaneous Squamous Cell Carcinoma of the Head and Neck
    Pride, Renee L. D.
    Lopez, Jonathan J.
    Brewer, Jerry D.
    Price, Daniel L.
    Otley, Clark C.
    Roenigk, Randall K.
    Arpey, Christopher J.
    Baum, Christian L.
    DERMATOLOGIC SURGERY, 2022, 48 (02) : 157 - 161
  • [22] Lymph node ratio as a prognostic factor in metastatic cutaneous head and neck squamous cell carcinoma
    Vasan, Kartik
    Low, Tsu-Hui
    Gupta, Ruta
    Ashford, Bruce
    Asher, Rebecca
    Gao, Kan
    Ch'ng, Sydney
    Palme, Carsten E.
    Clark, Jonathan R.
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2018, 40 (05): : 993 - 999
  • [23] Surgical management of cutaneous squamous cell carcinoma of the head and neck
    Baker, NJ
    Webb, AAC
    Macpherson, D
    BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 2001, 39 (02): : 87 - 90
  • [24] RESULTS OF SURGICAL RESECTION OF PULMONARY METASTASES OF SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK
    FINLEY, RK
    VERAZIN, GT
    DRISCOLL, DL
    BLUMENSON, LE
    TAKITA, H
    BAKAMJIAN, V
    SAKO, K
    HICKS, W
    PETRELLI, NJ
    SHEDD, DP
    AMERICAN JOURNAL OF SURGERY, 1992, 164 (06): : 594 - 598
  • [25] The impact of surgical margins in managing regional metastases in cutaneous squamous cell carcinoma of the head and neck
    Braude, Rachel
    Manzie, Timothy G. H.
    Clark, Jonathan R.
    Shannon, Kerwin
    Palme, Carsten E.
    Elliott, Michael
    Wykes, James
    Ch'ng, Sydney
    Gupta, Ruta
    Cheung, Veronica
    Low, Tsu-Hui
    LARYNGOSCOPE, 2025,
  • [26] Outcomes of cutaneous squamous cell carcinoma of the head and neck with parotid metastases
    McDowell, Lachlan J.
    Tan, Tze-Jian
    Bressel, Mathias
    Estall, Vanessa
    Kleid, Stephen
    Corry, June
    Johnston, Meredith L.
    JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, 2016, 60 (05) : 668 - 676
  • [27] Soft Tissue Metastases in Head and Neck Cutaneous Squamous Cell Carcinoma
    Mooney, Craig P.
    Gao, Kan
    Clark, Jonathan R.
    Gupta, Ruta
    Shannon, Kerwin
    Palme, Carsten E.
    Ebrahimi, Ardalan
    Ch'ng, Sydney
    Low, Tsu-Hui
    LARYNGOSCOPE, 2021, 131 (04): : E1209 - E1213
  • [28] Multivariate analysis of potential risk factors for lymph node metastasis in patients with cutaneous squamous cell carcinoma of the head and neck
    Haisma, Marjolijn S.
    Plaat, Boudewijn E. C.
    Bijl, Hendrik P.
    Roodenburg, Jan L. N.
    Diercks, Gilles F. H.
    Romeijn, Tonnis R.
    Terra, Jorrit B.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 75 (04) : 722 - 730
  • [29] High-risk cutaneous squamous cell carcinoma of the head and neck - Results from 266 treated patients with metastatic lymph node disease
    Veness, Michael J.
    Palme, Carsten E.
    Morgan, Gary J.
    CANCER, 2006, 106 (11) : 2389 - 2396
  • [30] SURGICAL-MANAGEMENT OF LYMPH-NODE METASTASES IN CUTANEOUS MELANOMA OF THE HEAD AND NECK
    SCHOUWENBURG, PF
    VREEBURG, G
    HILGERS, FJM
    CLINICAL OTOLARYNGOLOGY, 1987, 12 (04): : 312 - 312