Early detection of pancreatic cancer in the era of precision medicine

被引：0

作者：

Ahmed, Taha M. ^{[1
]}

Kawamoto, Satomi ^{[1
]}

Lopez-Ramirez, Felipe ^{[1
]}

Yasrab, Mohammad ^{[1
]}

Hruban, Ralph H. ^{[2
]}

Fishman, Elliot K. ^{[1
]}

Chu, Linda C. ^{[1
]}

机构：

[1] Johns Hopkins Univ Hosp, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA

[2] Johns Hopkins Univ, Sol Goldman Pancreat Canc Res Ctr, Dept Pathol, Sch Med, Baltimore, MD USA

来源：

ABDOMINAL RADIOLOGY | 2024年 / 49卷 / 10期

关键词：

Pancreatic ductal adenocarcinoma; Cancer screening; CT; MRI; Artificial intelligence; Liquid biopsy; CIRCULATING TUMOR-CELLS; METHYLATION-BASED BIOMARKERS; DUCTAL ADENOCARCINOMA; HIGH-RISK; DNA; DIAGNOSIS; CT; PROGRESSION; SIGNATURE; EXOSOMES;

D O I：

10.1007/s00261-024-04358-w

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related mortality and it is often diagnosed at advanced stages due to non-specific clinical presentation. Disease detection at localized disease stage followed by surgical resection remains the only potentially curative treatment. In this era of precision medicine, a multifaceted approach to early detection of PDAC includes targeted screening in high-risk populations, serum biomarkers and "liquid biopsies", and artificial intelligence augmented tumor detection from radiologic examinations. In this review, we will review these emerging techniques in the early detection of PDAC.

引用

页码：3559 / 3573

页数：15

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