Novel (2-Oxoindolin-3-ylidene)methyl)-1H-pyrazole and their fused derivatives: Design, synthesis, antimicrobial evaluation, DFT, chemical approach, in silico ADME and molecular docking studies

被引:0
|
作者
El-Qaliei, Mohamed I.H. [1 ]
Mousa, Sayed A.S. [1 ]
Mahross, M.H. [1 ]
Hassane, A.M.A. [2 ]
Gad-Elkareem, Mohamed A.M. [1 ]
Anouar, El Hassane [3 ]
Snoussi, Mejdi [4 ,5 ]
Aouadi, Kaïss [6 ,7 ]
Kadri, Adel [8 ,9 ]
机构
[1] Chemistry Department, Faculty of Science, Al-Azhar University, Assiut Branch, Assiut,71524, Egypt
[2] Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Assiut Branch, Assiut,71524, Egypt
[3] Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj,11942, Saudi Arabia
[4] Department of Biology, College of Science, University of Ha'il City 2440, Hail, P.O. 2440, Saudi Arabia
[5] Laboratory of Genetics, Biodiversity and Valorization of Bio-resources (LR11ES41), University of Monastir, Higher Institute of Biotechnology of Monastir, Avenue Tahar Haddad, Monastir,BP74, 5000, Tunisia
[6] Department of Chemistry, College of Science, Qassim University, Buraidah,51452, Saudi Arabia
[7] University of Monastir, Faculty of Sciences of Monastir, Avenue of the Environment, Monastir,5019, Tunisia
[8] Faculty of Science of Sfax, Department of Chemistry, University of Sfax, B.P. 1171, Sfax,3000, Tunisia
[9] Department of Chemistry, Faculty of Science and Arts of Baljurashi, Albaha University, Saudi Arabia
关键词
D O I
暂无
中图分类号
学科分类号
摘要
70
引用
收藏
相关论文
共 50 条
  • [41] SYNTHESIS, DOCKING, INVITRO ANTIMICROBIAL AND ANTIMALARIAL EVALUATION OF NOVEL 2-(FURAN-3-YL)-1 H-BENZO [d] IMIDAZOLE ANCHORED WITH FLAVONE AND PYRAZOLE DERIVATIVES
    Gadakh, Amol V.
    Rindhe, Sahebrao S.
    Karale, Bhausaheb. K.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 24 (02) : 213 - 222
  • [42] Synthesis of Novel Substituted Phenyl-3-Hydrazinyl-Quinoxaline-2-Amine Derivatives: Evaluation of Antimicrobial Activity and Its Molecular Docking Studies
    Paliwal, Sarvesh
    Sharma, Swapnil
    Dwivedi, Jaya
    Mishra, Achal
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 54 (06) : 3689 - 3695
  • [43] Synthesis of Novel 1-(5-(Benzylsulfinyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)-thiourea/urea Derivatives and Evaluation of Their Antimicrobial Activities
    Mannam, Madhava Rao
    Srimurugan, S.
    Kumar, Pramod
    Prasad, R. S. K.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (08) : 2179 - 2191
  • [44] Synthesis, antimicrobial, analgesic activity, and molecular docking studies of novel 1-(5,7-dichloro-1,3-benzoxazol-2-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde derivatives
    Jayanna, N. D.
    Vagdevi, H. M.
    Dharshan, J. C.
    Raghavendra, R.
    Telkar, Sandeep B.
    MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (12) : 5814 - 5822
  • [45] Synthesis, antimicrobial, analgesic activity, and molecular docking studies of novel 1-(5,7-dichloro-1,3-benzoxazol-2-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde derivatives
    N. D. Jayanna
    H. M. Vagdevi
    J. C. Dharshan
    R. Raghavendra
    Sandeep B. Telkar
    Medicinal Chemistry Research, 2013, 22 : 5814 - 5822
  • [46] Synthesis, antitumor activity, antimicrobial evaluation and molecular docking studies of some hydrazone, 1,3,4-oxadiazole, 1,2,4-triazole and pyrazole derivatives bearing nicotinoyl moiety
    Farghaly, Abdel-Rahman
    Ahmed, Saleh A.
    Ismail, Khatib S.
    Ibrahim, Diaa
    Amri, Nasser
    Elgogary, Sameh
    RESULTS IN CHEMISTRY, 2024, 7
  • [47] Design, synthesis of novel (Z)-2-(3-(4-((3-benzyl-2,4dioxothiazolidin-5-ylidene)methyl)-1-phenyl-1H-pyrazol-3-yl) phenoxy)-N-arylacetamide derivatives: Evaluation of cytotoxic activity and molecular docking studies
    Kolluri, Prashanth Kumar
    Gurrapu, Nirmala
    Subhashini, N. J. P.
    Putta, Shravani
    Singh, Surya Sathyanarayana
    Vani, Tamalapakula
    Manga, Vijjulatha
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1202
  • [48] Design, synthesis, biological evolution and in silico studies of a novel 1,2,3,4-tetrazole fused with 1,3,4-thiadiazole-2-amine derivatives
    Rajeswari, Muthirevula
    Nagaraju, Begari
    Yasmintaj, Shaik
    Muralidhar, Pamerla
    Rao, Chunduri Venkata
    Karunakar, Prashantha
    Maddila, Suresh
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2024, 61 (07) : 1116 - 1124
  • [49] Hybrids of thiazolidinone with 1,2,3-triazole derivatives: design, synthesis, biological evaluation, in silico studies, molecular docking, molecular dynamics simulations, and ADMET profiling
    Bimoussa, Abdoullah
    Fawzi, Mourad
    Oubella, Ali
    Ejaz, Syeda Abida
    Sajjad Bilal, Muhammad
    Labd Taha, Mohamed
    Auhmani, Aziz
    Morjani, Hamid
    Robert, Anthony
    Riahi, Abdelkhalek
    Ait Itto, My Youssef
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 41 (21): : 11987 - 11999
  • [50] Design, synthesis, DFT calculations, molecular docking and antimicrobial activities of novel cobalt, chromium metal complexes of heterocyclic moietybased 1,3,4-oxadiazole derivatives
    Rohand, Taoufik
    Ayouchia, Hicham Ben El
    Achtak, Hafid
    Ghaleb, Adib
    Derin, Yavuz
    Tutar, Ahmet
    Tanemura, Kiyoshi
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2022, 40 (22): : 11837 - 11850