Novel (2-Oxoindolin-3-ylidene)methyl)-1H-pyrazole and their fused derivatives: Design, synthesis, antimicrobial evaluation, DFT, chemical approach, in silico ADME and molecular docking studies

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作者
El-Qaliei, Mohamed I.H. [1 ]
Mousa, Sayed A.S. [1 ]
Mahross, M.H. [1 ]
Hassane, A.M.A. [2 ]
Gad-Elkareem, Mohamed A.M. [1 ]
Anouar, El Hassane [3 ]
Snoussi, Mejdi [4 ,5 ]
Aouadi, Kaïss [6 ,7 ]
Kadri, Adel [8 ,9 ]
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[1] Chemistry Department, Faculty of Science, Al-Azhar University, Assiut Branch, Assiut,71524, Egypt
[2] Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Assiut Branch, Assiut,71524, Egypt
[3] Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj,11942, Saudi Arabia
[4] Department of Biology, College of Science, University of Ha'il City 2440, Hail, P.O. 2440, Saudi Arabia
[5] Laboratory of Genetics, Biodiversity and Valorization of Bio-resources (LR11ES41), University of Monastir, Higher Institute of Biotechnology of Monastir, Avenue Tahar Haddad, Monastir,BP74, 5000, Tunisia
[6] Department of Chemistry, College of Science, Qassim University, Buraidah,51452, Saudi Arabia
[7] University of Monastir, Faculty of Sciences of Monastir, Avenue of the Environment, Monastir,5019, Tunisia
[8] Faculty of Science of Sfax, Department of Chemistry, University of Sfax, B.P. 1171, Sfax,3000, Tunisia
[9] Department of Chemistry, Faculty of Science and Arts of Baljurashi, Albaha University, Saudi Arabia
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