Single-nucleotide variant of PIK3CA H1047R gene assay by CRISPR/Cas12a combined with rolling circle amplification

被引：0
|
作者：
Cao, Gaihua [1 ]
Chen, Xiaolong [1 ]
Deng, Yuanyi [1 ]
Nie, Fuping [1 ,2 ]
Liu, Yin [1 ]
Wang, Guoming [2 ]
Huo, Danqun [1 ,3 ]
Hou, Changjun [1 ]
机构：
[1] Key Laboratory of Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing,400044, China
[2] Key Laboratory of Cattle Diseases Detection (Chongqing), Diagnosis and Testing Laboratory of Lumpy Skin Disease, Chongqing Customs Technology Center, Chongqing,400044, China
[3] Chongqing Key Laboratory of Bio-perception & Intelligent Information Processing, School of Microelectronics and Communication Engineering, Chongqing University, Chongqing,400044, China
来源：
Analytica Chimica Acta | 2021年 / 1182卷
基金：
中国国家自然科学基金;
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 46 条
  • [31] Association of PIK3CA H1047R and STK11 F354L mutations with response to neoadjuvant chemoradiotherapy and survival in esophageal cancer.
    Hsu, Po Kuei
    Chou, Teh-Ying
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
  • [32] H1047R PIK3CA mutant enhances HER2-mediated transformation via heregulin production and activation of HER3 in human mammary epithelial cells
    Chakrabarty, Anindita
    Rexer, Brent
    Engelman, Jeffrey
    Arteaga, Carlos
    CANCER RESEARCH, 2009, 69
  • [33] PIK3CA hotspot mutations p. H1047R and p. H1047L sensitize breast cancer cells to thymoquinone treatment by regulating the PI3K/Akt1 pathway
    Ju Zhou
    Saber Imani
    Marzieh Dehghan Shasaltaneh
    Shuguang Liu
    Tao Lu
    Junjiang Fu
    Molecular Biology Reports, 2022, 49 : 1799 - 1816
  • [34] PIK3CA hotspot mutations p. H1047R and p. H1047L sensitize breast cancer cells to thymoquinone treatment by regulating the PI3K/Akt1 pathway
    Zhou, Ju
    Imani, Saber
    Shasaltaneh, Marzieh Dehghan
    Liu, Shuguang
    Lu, Tao
    Fu, Junjiang
    MOLECULAR BIOLOGY REPORTS, 2022, 49 (03) : 1799 - 1816
  • [35] PIK3CA somatic alterations in 412 chinese invasive breast cancers: Higher frequency of mutant H1047R detected by next generation sequencing compared to breast cancer in caucasians
    Jia, Minghan
    Liao, Ning
    Chen, Bo
    Zhang, Guochun
    Wang, Yulei
    Chen, Xiaoqing
    Guo, Liping
    Cao, Li
    Mok, Hsiaopei
    Ren, Chongyang
    Li, Kai
    Li, Cheukfai
    Wen, Lingzhu
    Lin, Jiali
    Wei, Guangnan
    Zhang, Zhou
    Balch, Charles M.
    CANCER RESEARCH, 2020, 80 (04)
  • [36] Sensitive Detection of PIK3CA Exon 20 H1047R Breast Cancer Based on Low-C ost Intercalary Dye SYBR Green I Real-T ime qPCR Assay
    Desriani
    Azamris
    Kustamadji, Primariadewi
    Abna, Inherni marti
    Ibadurrahman, Irsyad
    Fuad, Asrul muhammad
    Nurdiani, Dini
    Yuliawati, Yuliawati
    Utami, Nuruliawaty
    Herawati, Neng
    Fitria, Najmiatul
    Warisman, Muhammad ali
    SAINS MALAYSIANA, 2024, 53 (11): : 3683 - 3693
  • [37] The H1047R PIK3CA oncogene induces a senescence-like state, pleiotropy and acute HSP90 dependency in HER2+mammary epithelial cells
    Chakrabarty, Anindita
    Surendran, Sreeraj
    Bhola, Neil E.
    Mishra, Vishnu
    Wani, Tasaduq Hussain
    Baghel, Khemraj
    Arteaga, Carlos L.
    Garg, Rohini
    Chowdhury, Goutam
    CARCINOGENESIS, 2019, 40 (10) : 1179 - 1190
  • [38] The PIK3CA H1047R Mutation Confers Resistance to BRAF and MEK Inhibitors in A375 Melanoma Cells through the Cross-Activation of MAPK and PI3K-Akt Pathways
    Candido, Saverio
    Salemi, Rossella
    Piccinin, Sara
    Falzone, Luca
    Libra, Massimo
    PHARMACEUTICS, 2022, 14 (03)
  • [39] Sensitive detection of CaMV35S based on exponential rolling circle amplification reaction and CRISPR/Cas12a using a portable 3D-printed visualizer
    Liu, Meilin
    Li, Xuheng
    Xu, Jingbing
    Zhou, Shiying
    Deng, Liyuan
    Men, Dianhui
    Duan, Yi
    Huo, Danqun
    Hou, Changjun
    MICROCHEMICAL JOURNAL, 2024, 205
  • [40] PIK3CA H1047R Mutation Associated with a Lower Pathological Complete Response Rate in Triple-Negative Breast Cancer Patients Treated with Anthracycline-Taxane-Based Neoadjuvant Chemotherapy
    Guo, Sanxing
    Loibl, Sibylle
    von Minckwitz, Gunter
    Darb-Esfahani, Silvia
    Lederer, Bianca
    Denkert, Carsten
    CANCER RESEARCH AND TREATMENT, 2020, 52 (03): : 689 - 696
12345