Preparation and Characterization of Nanostructured Lipid Carrier Co-loaded Resveratrol and Linseed Oil

被引：0
|
作者：
Li T. [1 ,2 ,3 ]
Huang J. [1 ,2 ,3 ]
Wang Q. [1 ,2 ,3 ]
Xia N. [1 ,2 ,3 ]
Xia Q. [1 ,2 ,3 ]
机构：
[1] School of Biological Science and Medical Engineering, State Key Laboratory of Bioelectronics, Southeast University, Nanjing
[2] National Demonstration Center for Experimental Biomedical Engineering Education, Southeast University, Nanjing
[3] Collaborative Innovation Center of Suzhou Nano Science and Technology, Suzhou, 215123, Jiangsu
来源：
Journal of Chinese Institute of Food Science and Technology | 2019年 / 19卷 / 09期
关键词：
Linseed oil; Nanostructured lipid carrier; Resveratrol;
D O I：
10.16429/j.1009-7848.2019.09.013
中图分类号：
学科分类号：
摘要：
The nanostructured lipid carrier(RL-NLC) was developed to encapsulate, protect and deliver resveratrol and linseed oil by the hot high pressure homogenization technology. The microstructure, physicochemical stability, antioxidant activity, in vitro release, accelerated lipid oxidation and other characteristics were analyzed. The particle size of RL-NLC was about 105 nm and the PDI was about 0.216. The spherical nanoparticles could be well dispersed in aqueous and could be stored for more than 3 months at 25℃ without light. Encapsulated resveratrol had better antioxidant activity and slower release rate in vitro than free resveratrol. In addition, it was found that the presence of the solid lipid core and resveratrol inhibited the oxidation of linseed oil in an accelerated storage experiment at 50℃. The carrier loaded resveratrol and linseed oil developed in this paper may have a good application prospect in the field of functional foods. © 2019, Editorial Office of Journal of CIFST. All right reserved.
引用
收藏
页码：109 / 115
页数：6
相关论文
共 13 条
  • [11] Maqsood S., Benjakul S., Comparative studies of four different phenolic compounds on in vitro antioxidative activity and the preventive effect on lipid oxidation of fish oil emulsion and fish mince, Food Chemistry, 119, 1, pp. 123-132, (2010)
  • [12] Chen F., Liang L., Zhang Z.P., Et al., Inhibition of lipid oxidation in nanoemulsions and filled microgels fortified with omega-3 fatty acids using casein as a natural antioxidant, Food Hydrocolloids, 63, pp. 240-248, (2017)
  • [13] Sun R., Zhao G.D., Ni S.L., Et al., Lipid based nanocarriers with different lipid compositions for topical delivery of resveratrol: Comparative analysis of characteristics and performance, Joumal of Drug Delivery Science and Technology, 24, 6, pp. 591-600, (2014)
12