Horner-Wadsworth-Emmons olefination for bioconjugation

被引：0
|
作者：
Aye, Yimon [1 ]
机构：
[1] Swiss Fed Inst Technol Lausanne EPFL, Lausanne, Switzerland
来源：
NATURE SYNTHESIS | 2024年 / 3卷 / 08期
关键词：
D O I：
10.1038/s44160-024-00571-z
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Through site-specific generation of intermediary reactive aldehydes, Horner-Wadsworth-Emmons olefination can now deliver selective functionalization of stable recombinant proteins and monoclonal antibodies, whilst preserving protein integrity.
引用
收藏
页码：935 / 936
页数：2
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