For industrial information physical systems (ICPS) with gap denial of service (DoS) attacks, an observer-based adaptive event-triggered stability control scheme was proposed. Firstly, an observer was constructed to estimate the unmeasured state of the system, and a new adaptive event-triggered communication scheme was adopted to save network resources. Secondly, an attack model was established based on the influence of intermittent DoS attacks on ICPS limited by frequency and duration. ICPS subjected to DoS attacks was divided into active DoS attack system and dormant DoS attack system, and the current attacked states were reconstructed by some successful trigger states. An attack compensation mechanism based on dynamic estimator was proposed to ensure the asymptotic stability of the system during active DoS attacks. Finally, the piecewise Lyapunov functional method, Jensen’s inequality and Schur’s complement lemma were used to obtain the stability conditions of the system. On this basis, a cooperative design scheme of adaptive event triggering parameters, observer gain and controller gain was proposed. The intermittent reactor system was used to simulate the stability of ICPS based on adaptive event triggering under intermittent DoS attack. The simulation results show that the adaptive event triggering strategy and the compensation mechanism based on the dynamic estimator can not only improve the stability of the system, but also effectively reduce the number of data transmission. The times of the system triggered by the static event triggering policy is about 4. 5 times that of the system triggered by the adaptive event triggering policy. © 2023 South China University of Technology. All rights reserved.