Systemic dendrimer delivery of triptolide to tumor-associated macrophages improves anti-tumor efficacy and reduces systemic toxicity in glioblastoma

被引：0
|
作者：
Liaw, Kevin [1 ,2 ]
Sharma, Rishi [1 ]
Sharma, Anjali [1 ]
Salazar, Sebastian [3 ]
Appiani La Rosa, Santiago [1 ,3 ]
Kannan, Rangaramanujam M. [1 ,2 ,4 ]
机构：
[1] Center for Nanomedicine, Department of Ophthalmology, Wilmer Eye Institute Johns Hopkins University School of Medicine, Baltimore,MD,21231, United States
[2] Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore,MD,21218, United States
[3] Department of Biomedical Engineering, Johns Hopkins University, Baltimore,MD,21218, United States
[4] Hugo W. Moser Research Institute at Kennedy Krieger, Inc., Baltimore,MD,21205, United States
来源：
Journal of Controlled Release | 2021年 / 329卷
关键词：
Tumors; -; Macrophages; Toxicity;
D O I：
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中图分类号：
学科分类号：
摘要：
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页码：434 / 444
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