A rapid synthesis of medicinally important spiropyrrolines has been achieved by the reaction of 1,3-indanediones, benzaldehyde, and (1-azidovinyl)benzene under catalyst- and reagent-free conditions. This is the first report to synthesize diverse spiropyrroline compounds from readily available feedstock materials under metal-free conditions.
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CSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, India
Singroha, Rekha
Onen, Patrick
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CSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, India
Onen, Patrick
Yadav, Usha
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CSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, India
Acad Sci & Innovat Res, Ghaziabad 201002, IndiaCSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, India
Yadav, Usha
Kant, Ruchir
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CSIR Cent Drug Res Inst, Biochem & Struct Biol Div, Lucknow 226031, IndiaCSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, India
Kant, Ruchir
Mohanan, Kishor
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CSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, India
Acad Sci & Innovat Res, Ghaziabad 201002, IndiaCSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, India