A rapid synthesis of medicinally important spiropyrrolines has been achieved by the reaction of 1,3-indanediones, benzaldehyde, and (1-azidovinyl)benzene under catalyst- and reagent-free conditions. This is the first report to synthesize diverse spiropyrroline compounds from readily available feedstock materials under metal-free conditions.
机构:
Univ Groningen, Dept Drug Design, Antonius Deusinglaan 1, NL-9713 AV Groningen, NetherlandsUniv Groningen, Dept Drug Design, Antonius Deusinglaan 1, NL-9713 AV Groningen, Netherlands
Chandgude, Ajay L.
Domling, Alexander
论文数: 0引用数: 0
h-index: 0
机构:
Univ Groningen, Dept Drug Design, Antonius Deusinglaan 1, NL-9713 AV Groningen, NetherlandsUniv Groningen, Dept Drug Design, Antonius Deusinglaan 1, NL-9713 AV Groningen, Netherlands