Suppression of USP8 sensitizes cells to ferroptosis via SQSTM1/p62-mediated ferritinophagy

被引：0

作者：

Lihong Liu ^{[1
]}

Birong Zheng ^{[1
]}

Manhui Luo ^{[1
]}

Jie Du ^{[1
]}

Fang Yang ^{[2
]}

Chuanxin Huang ^{[2
]}

Zengyi Ma ^{[3
]}

Chunmei Li ^{[1
]}

Deyin Guo ^{[1
]}

Hong Peng ^{[1
]}

机构：

[1] MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University

[2] Shanghai Institute of Immunology and Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine

[3] Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan

来源：

Protein & Cell | 2023年 / 14卷 / 03期

关键词：

D O I：

暂无

中图分类号：

Q255 [细胞的衰老与死亡];

学科分类号：

摘要：

<正>Dear Editor,Ferroptosis is a newly discovered form of regulated cell death characterized by increased intracellular iron accumulation and subsequent lipid peroxidation (Dixon et al., 2012). Studies have revealed that ferroptosis plays an important role in multiple physiological and pathological processes including degenerative diseases, carcinogenesis, and cancer immunotherapy (Hassannia et al., 2019, Wang et al., 2019).

引用

页码：230 / 254

页数：25

共 50 条

[31] Resveratrol Promotes Autophagic Cell Death in Chronic Myelogenous Leukemia Cells via JNK-Mediated p62/SQSTM1 Expression and AMPK Activation
Puissant, Alexandre
Robert, Guillaume
Fenouille, Nina
Luciano, Frederic
Cassuto, Jill-Patrice
Raynaud, Sophie
Auberger, Patrick
CANCER RESEARCH, 2010, 70 (03) : 1042 - 1052
[32] Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy
Fan, Weiliang
Tang, Zaiming
Chen, Dandan
Moughon, Diana
Ding, Xiaojun
Chen, She
Zhu, Muyuan
Zhong, Qing
AUTOPHAGY, 2010, 6 (05) : 614 - 621
[33] Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells
Wu, Yanjun
Li, Yanping
Wang, Baoya
He, Xin
Li, Yunxiao
Wu, Bo
Yu, Ganggang
Wang, Haoyan
Xu, Bo
LIFE SCIENCES, 2018, 211 : 270 - 278
[34] Monitoring autophagic flux using p62/SQSTM1 based luciferase reporters in glioma cells
Zhang Min
Yao Ting
Gong Mingtao
Tang Xiaofei
Yan Dong
Zhang Chenguang
Ding Wei
EXPERIMENTAL CELL RESEARCH, 2018, 363 (01) : 84 - 94
[35] Depletion of autophagy receptor p62/SQSTM1 enhances the efficiency of gene delivery in mammalian cells
Tsuchiya, Megumi
Ogawa, Hidesato
Koujin, Takako
Kobayashi, Shouhei
Mori, Chie
Hiraoka, Yasushi
Haraguchi, Tokuko
FEBS LETTERS, 2016, 590 (16) : 2671 - 2680
[36] Autophagy-mediated upregulation of cytoplasmic claudin 1 stimulates the degradation of SQSTM1/p62 under starvation
Kim, Jaewhan
Choi, Sunkyung
Kim, Jong Ok
Kim, Kee K.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 496 (01) : 159 - 166
[37] p62/SQSTM1 is required for exercise training-mediated regulation of antioxidant enzymes in skeletal muscle
Yamada, Mami
Iwata, Masahiro
Okutsu, Mitsuharu
FASEB JOURNAL, 2018, 32 (01):
[38] Normal pancreatic β-cell function in mice with RIP-Cre-mediated inactivation of p62/SQSTM1
Honda, Akira
Komiya, Koji
Hara, Akemi
Fukunaka, Ayako
Suzuki, Luka
Miyatsuka, Takeshi
Ogihara, Takeshi
Fujitani, Yoshio
Watada, Hirotaka
ENDOCRINE JOURNAL, 2018, 65 (01) : 83 - 89
[39] mTOR-mediated p62/SQSTM1 stabilization confers a robust survival mechanism for ovarian cancer
Tamura, Tomohiro
Nagai, Shimpei
Masuda, Kenta
Imaeda, Keiyo
Sugihara, Eiji
Yamasaki, Juntaro
Kawaida, Miho
Otsuki, Yuji
Suina, Kentaro
Nobusue, Hiroyuki
Akahane, Tomoko
Chiyoda, Tatsuyuki
Kisu, Iori
Kobayashi, Yusuke
Banno, Kouji
Sakurada, Kazuhiro
Okita, Hajime
Yamaguchi, Rui
Ahmed, Ahmed Ashour
Yamagami, Wataru
Saya, Hideyuki
Aoki, Daisuke
Nagano, Osamu
CANCER LETTERS, 2025, 616
[40] p62/SQSTM1 is involved in cisplatin resistance in human ovarian cancer cells via the Keap1-Nrf2-ARE system
Xia, Meihui
Yu, Huimei
Gu, Shuang
Xu, Ye
Su, Jing
Li, Hongyan
Kang, Jinsong
Cui, Manhua
INTERNATIONAL JOURNAL OF ONCOLOGY, 2014, 45 (06) : 2341 - 2348

← 1 2 3 4 5 →