Design and redesign journey of a drug for transthyretin amyloidosis

被引：0
|
作者：
Francisca Pinheiro
Salvador Ventura
机构：
[1] Universitat Autònoma de Barcelona
[2] Institut de Biotecnologia i Biomedicina
[3] Departament de Bioquímica i Biologia Molecular
来源：
Neural Regeneration Research | 2025年 / 20卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R91 [药物基础科学];
学科分类号：
1007 ;
摘要：
The misfolding and subsequent aggregation of proteins into amyloid fibrils underlie the onset of a variety of human disorders collectively known as amyloidosis.Transthyretin (TTR) is one of the> 30 amyloidogenic proteins identified to date and is associated with a group of highly debilitating and life-threatening disorders called TTR amyloidosis (ATTR).ATTR comprises senile systemic amyloidosis,
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页码：1096 / 1097
页数：2
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