SYNTHESIS OF (PLUS-OR-MINUS) MYO-INOSITOL-1-O-METHYLPHOSPHONATE-4,5-BIS(PHOSPHATE), AN ANALOG OF D-MYO-INOSITOL-1,4,5-TRIS(PHOSPHATE)

被引：6

作者：

SCHMITT, L ^{[1
]}

SPIESS, B ^{[1
]}

SCHLEWER, G ^{[1
]}

机构：

[1] FAC PHARM STRASBOURG,PHARMACOCHIM MOLEC LAB,74 ROUTE RHIN,F-67401 ILLKIRCH GRAFFENS,FRANCE

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)61597-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of (+/-)myo-inositol-1-Ounderbar-methylphosphonate-4,5-bis(phosphate) is reported. This compound is an analogue of D-myo-inositol-1,4,5-tris(phosphate) in which the phosphate group in position 1 is replaced by a methyl phosphonate function and where the important vicinal phosphate groups in positions 4 and 5 am preserved.

引用

页码：7059 / 7060

页数：2

共 50 条

[21] SYNTHESIS OF DL-MYO-INOSITOL 1-PHOSPHATE AND ITS THIOPHOSPHATE ANALOG
METSCHIES, T
SCHULTZ, C
JASTORFF, B
TETRAHEDRON LETTERS, 1988, 29 (32) : 3921 - 3922
[22] 1D-1-O-tert-Butyldiphenylsilyl-2,3,6-O-tris(methoxymethylene)-myo-inositol-4,5-bis(dibenzylphosphate)
Anderson, Regan J.
Gainsford, Graeme J.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O900 - U3395
[23] DL-MYO-INOSITOL 1,2,4,5-TETRAKISPHOSPHATE, A POTENT ANALOG OF D-MYO-INOSITOL 1,4,5-TRISPHOSPHATE
HIRATA, M
NARUMOTO, N
WATANABE, Y
KANEMATSU, T
KOGA, T
OZAKI, S
MOLECULAR PHARMACOLOGY, 1994, 45 (02) : 271 - 276
[24] Inframolecular protonation process of 6-modified myo-inositol 1,4,5-tris(phosphates):: substitution effects on the cooperativity between the phosphate groups
Felemez, M
Ballereau, S
Schlewer, G
Spiess, B
NEW JOURNAL OF CHEMISTRY, 2000, 24 (08) : 631 - 638
[25] SYNTHESIS OF (+/-)-MYO-INOSITOL 1,4,5-TRISPHOSPHATE AND THE NOVEL ANALOG (+/-)-MYO-INOSITOL 1,4-BISPHOSPHATE 5-PHOSPHOROTHIOATE
NOBLE, NJ
COOKE, AM
POTTER, BVL
CARBOHYDRATE RESEARCH, 1992, 234 : 177 - 187
[26] SYNTHESIS OF 1D-4-O-BENZYL-MYO-INOSITOL, AND 1L-4-O-BENZYL-MYO-INOSITOL, 1D-4-O-ALPHA-L-FUCOPYRANOSYL-MYO-INOSITOL (IDENTICAL TO A NATURAL GLYCOSIDE), AND 1L-4-O-ALPHA-L-FUCOPYRANOSYL-MYO-INOSITOL
GAREGG, PJ
LINDBERG, B
KVARNSTROM, I
SVENSSON, SCT
CARBOHYDRATE RESEARCH, 1985, 139 (JUN) : 209 - 215
[27] A SHORT STEP SYNTHESIS OF OPTICALLY-ACTIVE MYOINOSITOL 1,3,4,5-TETRAKIS(PHOSPHATE) AND MYOINOSITOL 1,4,5-TRIS(PHOSPHATE) FROM 1,3,5-TRI-O-BENZOYL-MYO-INOSITOL
WATANABE, Y
FUJIMOTO, T
SHINOHARA, T
OZAKI, S
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (06) : 428 - 429
[28] Inframolecular protonation process of myo-inositol 1,4,5-tris(phosphate) and related compounds:: Dynamics of the intramolecular interactions and evidence of C-H•••O hydrogen bending
Felemez, M
Bernard, P
Schlewer, G
Spiess, B
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (13) : 3156 - 3165
[29] An efficient route to optically active inositol derivatives via the resolution of myo-inositol 1,3,5-orthoformate:: a short synthesis of D-myo-inositol-4-phosphate
Sureshan, KM
Watanabe, Y
TETRAHEDRON-ASYMMETRY, 2004, 15 (07) : 1193 - 1198
[30] A convenient synthesis of D-myo-inositol 1,4,5-trisphosphate (D-IP3), L-myo-inositol 1,4,5-trisphosphate (L-IP3), and a D-myo-inositol H-phosphonate.
Leung, LW
Bittman, R
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 214 : 35 - CARB

← 1 2 3 4 5 →