Peyronie's disease and erectile dysfunction: Report of 25 cases

Objectives: To identify and characterize erectile dysfunction in patients treated for Peyronie's disease (PD). Patients and methods: This single-center prospective study gathering 25 patients treated for PD was carried out in a Senegalese hospital between January 2012 and December 2013. The variables studied were: age, presence or not of erectile dysfunction according to the International Index of Erectile Function 5 (IIEF5), comorbidity, psychological profile, presence of Peyronie plaques, degree and direction of the curve, whether or not penile intromission was possible and treatment of erectile dysfunction. Results: The patients' mean age was 57 +/- 8.7 years. Eleven patients had erectile dysfunction (44%), 3 during the acute phase and 8 in the aftermath. The IIEF-5 score was 16.5 +/- 4.3. Comorbid conditions such as hypertension and diabetes were noted in 13 patients (52%). The size of most plaques was <= 3 cm. The average degree of curvature was 33.6. +/- 16.4.. The majority of patients (52%) were able to penetrate during intercourse without difficulty. A curvature of 45. and more had an adverse impact on intromission during sexual intercourse. Anxiety was reported in 19 patients (76%), 9 of whom suffered from insufficient erection. Treatment of erectile dysfunction consisted of the administration of sildenafil 50 mg which led to an improvement of the IIEF-5 score in most patients. Conclusion: PD may affect the patient's sex life. The erectile function disorder can be linked to the disease itself and/or to patient's underlying conditions. (C) 2015 Pan African Urological Surgeons' Association. Production and hosting by Elsevier B.V. All rights reserved.