PRODUCTION OF CYTOLETHAL DISTENDING TOXIN (CLDT) BY CAMPYLOBACTER-FETUS SUBSP FETUS ISOLATED FROM CALVES

被引：20
|
作者：
OHYA, T
TOMINAGA, K
NAKAZAWA, M
机构：
[1] YAMAGUCHI PREFECTURAL CHUBU LIVESTOCK HYG SERV CTR,KAGAWA,YAMAGUCHI 754,JAPAN
[2] NATL INST ANIM HLTH,KYUSHU BRANCH LAB,KAGOSHIMA 89101,JAPAN
来源：
JOURNAL OF VETERINARY MEDICAL SCIENCE | 1993年 / 55卷 / 03期
关键词：
CALF; CAMPYLOBACTER-FETUS SUBSP FETUS; CYTOTOXIN;
D O I：
10.1292/jvms.55.507
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Cytolethal distending toxin (CLDT) production by Campylobacter fetus subsp. fetus isolated from calves was examined using CHO cells. Twenty-five of the 26 strains tested were positive for CLDT with titer of ranging 1:8 to 1:2,048. CLDT positive strains were divided into low and high cytotoxin titer groups. Isolates from diarrhea cases tended to produce a significant amount of CLDT compared with isolates from liver. CLDT produced by C. fetus showed no effect on Y-1 cells and was heat-labile and trypsin-sensitive.
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页码：507 / 509
页数：3
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