THE MOLECULAR ELECTROSTATIC POTENTIAL AND DRUG DESIGN

被引：0
|
作者：
PEPE, G [1 ]
SIRI, D [1 ]
REBOUL, JP [1 ]
机构：
[1] UNIV AIX MARSEILLE 2, GERCTOP, F-13388 MARSEILLE 5, FRANCE
来源：
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM | 1992年 / 88卷
关键词：
D O I：
暂无
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The molecular electrostatic potential (MEP) is now a classical tool in chemical activity analysis, especially in drug design. In this paper we discuss, from different MEP applications in drug studies, significant results obtained over the last few years. This analysis led us to define how the MEP can be used in drug design, and the limits of its application, whatever the accuracy of the method used to calculate it.
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页码：175 / 185
页数：11
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