HOMOZYGOUS ALPHA-1-ANTITRYPSIN DEFICIENCY (PIZZ) AND BRONCHIAL-ASTHMA IN CHILDHOOD - IS THERE A CONNECTION

被引：0

作者：

NIGGEMANN, B ^{[1
]}

CLAUSSEN, M ^{[1
]}

KOEPP, P ^{[1
]}

机构：

[1] UNIV HAMBURG,KINDERKLIN EPPENDORF,W-2000 HAMBURG 13,GERMANY

来源：

KLINISCHE PADIATRIE | 1992年 / 204卷 / 02期

关键词：

D O I：

10.1055/s-2007-1025330

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Ten children and adolescents (aged four to 21 years) with the homozygous form of alpha-1-antitrypsin deficiency (PiZZ) were investigated with regard to obstructive airway disease. Besides the recording of the history, tests of lung function and allergy tests were performed. It was shown that bronchial asthma occurred in three out ot ten patients. However, we could not demonstrate any statistically significant increased incidence of bronchial asthma in our unselected PiZZ-patients compared to the overall population. There was no indication of emphysema in any of the nine patients.

引用

页码：98 / 101

页数：4

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