HOMOZYGOUS ALPHA-1-ANTITRYPSIN DEFICIENCY (PIZZ) AND BRONCHIAL-ASTHMA IN CHILDHOOD - IS THERE A CONNECTION

被引：0
|
作者：
NIGGEMANN, B [1 ]
CLAUSSEN, M [1 ]
KOEPP, P [1 ]
机构：
[1] UNIV HAMBURG,KINDERKLIN EPPENDORF,W-2000 HAMBURG 13,GERMANY
来源：
KLINISCHE PADIATRIE | 1992年 / 204卷 / 02期
关键词：
D O I：
10.1055/s-2007-1025330
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Ten children and adolescents (aged four to 21 years) with the homozygous form of alpha-1-antitrypsin deficiency (PiZZ) were investigated with regard to obstructive airway disease. Besides the recording of the history, tests of lung function and allergy tests were performed. It was shown that bronchial asthma occurred in three out ot ten patients. However, we could not demonstrate any statistically significant increased incidence of bronchial asthma in our unselected PiZZ-patients compared to the overall population. There was no indication of emphysema in any of the nine patients.
引用
收藏
页码：98 / 101
页数：4
相关论文
共 50 条
  • [1] BRONCHIAL-ASTHMA AND HOMOZYGOUS ALPHA-1-ANTITRYPSIN DEFICIENCY (PIZZ) IN 3 MEMBERS OF A FAMILY
    NIGGEMANN, B
    ALBANI, M
    KLINISCHE PADIATRIE, 1989, 201 (05): : 412 - 415
  • [2] ALPHA-1-ANTITRYPSIN PHENOTYPES AND BRONCHIAL-ASTHMA
    MONTESEIRIN, J
    PRADOS, M
    CONDE, J
    CHEST, 1994, 105 (06) : 1905 - 1906
  • [3] UNEQUAL DEVELOPMENT OF EMPHYSEMA IN 2 BROTHERS WITH HOMOZYGOUS ALPHA-1-ANTITRYPSIN DEFICIENCY (PIZZ)
    MEISTER, R
    POTT, G
    WITTING, C
    ATEMWEGS-UND LUNGENKRANKHEITEN, 1984, 10 (12) : 623 - 628
  • [4] Survival in severe alpha-1-antitrypsin deficiency (PiZZ)
    Hanan A Tanash
    Peter M Nilsson
    Jan-Åke Nilsson
    Eeva Piitulainen
    Respiratory Research, 11
  • [5] Survival in severe alpha-1-antitrypsin deficiency (PiZZ)
    Tanash, Hanan A.
    Nilsson, Peter M.
    Nilsson, Jan-Ake
    Piitulainen, Eeva
    RESPIRATORY RESEARCH, 2010, 11
  • [6] EVALUATION OF DANAZOL THERAPY FOR PATIENTS WITH PIZZ ALPHA-1-ANTITRYPSIN DEFICIENCY
    WEWERS, MD
    GADEK, JE
    KEOGH, BA
    FELLS, GA
    CRYSTAL, RG
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1986, 134 (03): : 476 - 480
  • [7] LIVER-DISEASE IN CHILDREN WITH PIZZ ALPHA-1-ANTITRYPSIN DEFICIENCY
    GHISHAN, FK
    GREENE, HL
    HEPATOLOGY, 1988, 8 (02) : 307 - 310
  • [8] PROGNOSIS OF HEPATOPATHY IN HOMOZYGOUS ALPHA-1-ANTITRYPSIN DEFICIENCY
    KARITZKY, D
    KUNZER, W
    MONATSSCHRIFT KINDERHEILKUNDE, 1977, 125 (05) : 472 - 473
  • [9] Is it Asthma, is it Bronchiectasis ... or is it an Alpha-1-Antitrypsin Deficiency?
    Amaro, Rosanel
    Huerta, Arturo
    Miravitlles, Marc
    ARCHIVOS DE BRONCONEUMOLOGIA, 2011, 47 (07): : 376 - 376
  • [10] SERUM ALPHA1-ANTITRYPSIN IN BRONCHIAL-ASTHMA
    SZCZEKLIK, A
    TUROWSKA, B
    CZERNIAW.G
    OPOLSKA, B
    NIZANKOWSKA, E
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1974, 109 (04): : 487 - 490
12345