Adherence of Candida albicans to Soft Denture Liners in Controlled Diabetic Patients

This study investigated the adhesion potential of Candida albicans on heat cured silicone based soft liner and acrylic resin-based liner in controlled diabetic patients. Twenty controlled male diabetic edentulous patients were precisely selected and thoroughly examined in an attempt to reduce human variables and eliminate any factor or habit that might adversely affect the results of this study. The patients were randomly divided into two equal groups: Group 1: Patients in this group were rehabilitated with maxillary heat cured acrylic dentures lined with silicone based soft liner "Molloplast B". Group 2: Patients in this group were rehabilitated with maxillary heat cured acrylic dentures lined with acrylic based soft liner "VERTEX soft". Sampling the tissue surface of the denture following the swab technique assessed the effect of each of the previously mentioned lining materials on candida counts. The swabs were taken from the fitting surface of denture base. The colonies were quantified according to the scale developed by Oslen and modified by Bergendal et al. The germ tube test was carried out to confirm the presence of Candida albicans. Samples were collected at time of denture insertion, one, three, six, and nine months after denture insertion. Data were tabulated and statistically analyzed. A significant increase in the calculated means of candida albicans growth was evident 3 months after denture insertion in the two studied groups. Three, six, and nine months after denture insertion confluent growth score (3) was detected in 100% the two studied groups. Statistical analysis of the data revealed higher significant values among cases wearing maxillary dentures lined with Molloplast B <0.05 compared to cases wearing maxillary dentures lined with liner "VERTEX soft".