TREATMENT OF EXPERIMENTAL CHRONIC OSTEOMYELITIS DUE TO STAPHYLOCOCCUS-AUREUS WITH AMPICILLIN SULBACTAM

被引：14
|
作者：
NORDEN, CW
BUDINSKY, A
机构：
[1] Department of Medicine, Montefiore Hospital, University of Pittsburgh School of Medicine, PA
来源：
JOURNAL OF INFECTIOUS DISEASES | 1990年 / 161卷 / 01期
关键词：
D O I：
10.1093/infdis/161.1.52
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Ampicillin/sulbactam was used for the treatment of experimental osteomyelitis due to Staphylococcus aureus in rabbits. Treatment with 200 mg/kg (ampicillin) three times a day sterilized 40% of infected rabbit bones. The results of 4 weeks of treatment with ampicillin/sulbactam for chronic experimental staphylococcal osteomyelitiswere comparable to those obtained previously with cephalothin and with oxacillin in previous studies and were not as good as those with clindamycin alone or combination therapy that included rifampin. © 1990 by The University of Chicago. All rights reserved.
引用
收藏
页码：52 / 53
页数：2
相关论文
共 50 条
  • [21] EFFICACY OF CLINDAMYCIN IN THE TREATMENT OF STAPHYLOCOCCUS-AUREUS OSTEOMYELITIS IN DOGS
    BRADEN, TD
    JOHNSON, CA
    WAKENELL, P
    TVEDTEN, HW
    MOSTOSKY, UV
    JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 1988, 192 (12): : 1721 - 1725
  • [22] INVITRO BACTERICIDAL ACTIVITY OF SULBACTAM PLUS AMPICILLIN AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS
    KAZMIERCZAK, A
    DUEZ, JM
    PECHINOT, A
    NORDMANN, P
    LABIA, R
    REVIEWS OF INFECTIOUS DISEASES, 1986, 8 : S549 - S554
  • [23] EFFICACY OF CEFOPERAZONE IN COMBINATION WITH SULBACTAM IN EXPERIMENTAL STAPHYLOCOCCUS-AUREUS ENDOCARDITIS IN RABBITS
    CHAMBERS, HF
    FOURNIER, MA
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1993, 32 (03) : 453 - 458
  • [24] THE PROMOTIONAL EFFECT OF BONE WAX ON EXPERIMENTAL STAPHYLOCOCCUS-AUREUS OSTEOMYELITIS
    NELSON, DR
    BUXTON, TB
    LUU, QN
    RISSING, JP
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1990, 99 (06): : 977 - 980
  • [25] COMPARATIVE-EVALUATION OF CEFAMANDOLE AND CEPHALOTHIN IN THE TREATMENT OF EXPERIMENTAL STAPHYLOCOCCUS-AUREUS OSTEOMYELITIS IN RABBITS
    MADER, JT
    WILSON, KJ
    JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1983, 65 (04): : 507 - 513
  • [26] COMPARATIVE-EVALUATION OF CEFAZOLIN AND CLINDAMYCIN IN THE TREATMENT OF EXPERIMENTAL STAPHYLOCOCCUS-AUREUS OSTEOMYELITIS IN RABBITS
    MADER, JT
    ADAMS, K
    MORRISON, L
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (10) : 1760 - 1764
  • [27] SEROLOGICAL DIAGNOSIS OF STAPHYLOCOCCUS-AUREUS OSTEOMYELITIS
    WHEAT, LJ
    WHITE, AC
    NORDEN, C
    JOURNAL OF CLINICAL MICROBIOLOGY, 1985, 21 (05) : 764 - 767
  • [28] COMBINED USE OF RIFAMPIN AND LINCOMYCIN IN THE TREATMENT OF ACUTE OSTEOMYELITIS AND POSTOPERATIVE INFECTIONS DUE TO STAPHYLOCOCCUS-AUREUS
    GILBERT, VE
    FARDON, DF
    BROWN, FF
    CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 1990, 47 (02): : 367 - 378
  • [29] TREATMENT OF OXACILLIN-TOLERANT STAPHYLOCOCCUS-AUREUS OSTEOMYELITIS IN RABBITS
    KHURANA, CM
    DEDDISH, PA
    CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 1988, 44 (03): : 415 - 420
  • [30] EXPERIMENTAL OSTEOMYELITIS DUE TO STAPHYLOCOCCUS-AUREUS OR PSEUDOMONAS-AERUGINOSA - A RADIOGRAPHIC-PATHOLOGICAL CORRELATIVE ANALYSIS
    NORDEN, CW
    MYEROWITZ, RL
    KELETI, E
    BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY, 1980, 61 (04): : 451 - 460
12345