CYCLOADDITION OF 2,3,4,5-TETRAHYDROPYRIDINE N-OXIDE TO VINYL ETHERS - ENANTIOSELECTIVE SYNTHESIS OF 2-(N-BENZYLPIPERIDIN-2-YL)ETHANOL

被引：29

作者：

CARRUTHERS, W

COGGINS, P

WESTON, JB

机构：

[1] WELLCOME RES LABS,RAVENS LANE,BERKHAMSTED HP4 2DY,HERTS,ENGLAND

[2] UNIV EXETER,DEPT CHEM,EXETER EX4 4RJ,DEVON,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 02期

关键词：

D O I：

10.1039/c39910000117

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The title compound has been obtained in high optical purity by cycloaddition of 2,3,4,5-tetrahydropyridine N-oxide and (R)-2,2-dimethyl-1-phenylpropyl vinyl ether followed by N-benzylation and reduction of the salt with lithium aluminium hydride.

引用

页码：117 / 118

页数：2

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