VIRIDANS STREPTOCOCCAL BACTEREMIA IN PATIENTS WITH NEUTROPENIA

被引：77
|
作者：
RICHARD, P
DELVALLE, GA
MOREAU, P
MILPIED, N
FELICE, MP
DAESCHLER, T
HAROUSSEAU, JL
RICHET, H
机构：
[1] HOP HOTEL DIEU,FAC CHIRURG DENT,F-44035 NANTES,FRANCE
[2] HOP HOTEL DIEU,SERV HEMATOL,F-44035 NANTES,FRANCE
来源：
LANCET | 1995年 / 345卷 / 8965期
关键词：
D O I：
10.1016/S0140-6736(95)90117-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Viridans streptococcal bacteraemia is frequent in neutropenic patients. 25 neutropenic patients with viridans streptococcal bacteraemia were compared with 64 control patients. Exposure to repeated chemotherapy or cytarabine were independent risk-factors for streptococcal bacteraemia. The use of carboxyureidopenicillins and stay in laminar-airflow rooms were protective. In a further cohort study of 49 patients, oral streptococci with the same ribotype as blood isolates were recovered from all 7 bacteraemic patients. The oral cavity is a portal of entry for viridans streptococci bacteraemia in neutropenic patients, especially after oral mucosal damage induced by repeated chemotherapy.
引用
收藏
页码：1607 / 1609
页数：3
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