A VARIANT (2-13) TRANSLOCATION IN RHABDOMYOSARCOMA

被引：10
|
作者：
DALCIN, P
BROCK, P
ALY, MS
CASTEELSVANDAELE, M
DEWEVER, I
VANDAMME, B
VANDENBERGHE, H
机构：
[1] CATHOLIC UNIV LEUVEN,CTR HUMAN GENET,HERESTR 49,B-3000 LOUVAIN,BELGIUM
[2] CATHOLIC UNIV LEUVEN,DEPT PEDIAT,B-3000 LOUVAIN,BELGIUM
[3] CATHOLIC UNIV LEUVEN,DEPT PATHOL,B-3000 LOUVAIN,BELGIUM
[4] CATHOLIC UNIV LEUVEN,DEPT SURG ONCOL,B-3000 LOUVAIN,BELGIUM
来源：
CANCER GENETICS AND CYTOGENETICS | 1991年 / 55卷 / 02期
关键词：
D O I：
10.1016/0165-4608(91)90077-8
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Cytogenetic analysis of a right buttock mass from a 5-year-old boy showed translocation between an inverted chromosome 1 and a chromosome 13 as the sole cytogenetic abnormality. The breakpoint 13q14 appears to be the same as in previously reported cases of rhabdomyosarcoma (mostly of the alveolar type), but does not show involvement of 2q37. We suggest that this translocation may be a variant of the classical t(2;13)(q37;q14) found in rhabdomyosarcoma.
引用
收藏
页码：191 / 195
页数：5
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