CRESCENTIC IGA NEPHROPATHY AS A MANIFESTATION OF HUMAN IMMUNE-DEFICIENCY VIRUS-INFECTION

被引：43
|
作者：
JINDAL, KK [1 ]
TRILLO, A [1 ]
BISHOP, G [1 ]
HIRSCH, D [1 ]
COHEN, A [1 ]
机构：
[1] DALHOUSIE UNIV,DEPT PATHOL,HALIFAX B3H 4H2,NS,CANADA
来源：
AMERICAN JOURNAL OF NEPHROLOGY | 1991年 / 11卷 / 02期
关键词：
CRESCENTIC NEPHROPATHY; IGA NEPHROPATHY; HIV NEPHROPATHY; CRESCENTIC IGA NEPHROPATHY;
D O I：
10.1159/000168292
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
A 37-year-old Caucasian male homosexual presented with hematuria and rapidly progressive acute renal failure. He was found to have proteinuria and microscopic hematuria as well as RBC casts. Investigations revealed polyclonal gammopathy with five times normal serum IgA levels as well as elevated serum IgG. Renal biopsy showed evidence of crescentic IgA nephropathy with ultrastructural changes of tubuloreticular inclusions described in HIV nephropathy. He was found to be positive for human immunodeficiency viral antibodies. Renal function improved during follow-up after two doses of 1 g each of methylprednisone. In our opinion, this is the first case of HIV-related crescentic IgA nephropathy. HIV testing should be performed more frequently in patients presenting with acute glomerular diseases.
引用
收藏
页码：147 / 150
页数：4
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