Micro-Spectrophotometric Determination And Cloud Point Extraction Of Sulphamethoxazole In Pure Form And Pharmaceutical Preparation

Two methods were proposed for the determination of sulfamethaczole in pure matter and pharmaceuticals. Simultaneously, with ease, simplicity and speed, the first method was based on sodium sulfate (sodium sulfate) by sodium nitrite in the acid medium at 5 degrees C followed by conjugation with beta naphthol in the base medium to form orange. And measured at 484 nm for the second method, the extraction was used at the cloud point and the surface material used was Triton X 114. Both methods obeyed the Per lambert law in a concentration range of 1-18 mu g / mL. The sandal sensitivity of the two methods was 0.023580-02341 mu g / ml and the detection limit was 0.118 and 0,24436 mu g / mL. The quantitative estimate was 0.023799 and 0.38708 mu g / ml. All the variables that affect the, process of interaction have been studied to improve the reaction conditions. Among these variables are the best acid, base, concentration of reagent, reagent and reaction time. The two methods were applied successfully. The results showed that the overlapping materials did not affect the measurement process