REDUCTION OF THE PYRIMIDINE RING - REGIOSELECTIVE AND STEREOSELECTIVE SYNTHESIS OF 1,3-DIAMINE DERIVATIVES

被引：0

作者：

BARLUENGA, J

TOMAS, M

KOUZNETSOV, V

JARDON, J

RUBIO, E

机构：

来源：

SYNLETT | 1991年 / 11期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Butyl-1,2-dihydropyrimidines 2 and 6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrimidines 3 are reduced with an excess of sodium borohydride in methanol to produce stereoselectively N,N'- and N,N-disubstituted 1,3-diamine derivatives 4 and 6, respectively. Partial reduction of 3 to fully saturated pyrrolo[1,2-a]pyrimidines 7 is accomplished using equimolecular amounts of sodium borohydride.

引用

页码：821 / 823

页数：3

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