ASYMMETRIC-SYNTHESIS OF S-(+)-4-AMINO-5-HEXYNOIC ACID

被引：18

作者：

MCALONAN, H ^{[1
]}

STEVENSON, PJ ^{[1
]}

机构：

[1] QUEENS UNIV BELFAST,SCH CHEM,BELFAST BT9 5AG,ANTRIM,NORTH IRELAND

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 01期

关键词：

D O I：

10.1016/0957-4166(94)00380-T

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

4-Amino-5-hexynoic acid is efficiently synthesised in eight steps (overall yield 10%) from commercially available (S)-glutamic acid. The key step was conversion of an aldehyde to an acetylene using diethylmethydiazophosphonate.

引用

页码：239 / 244

页数：6

共 50 条

[31] ASYMMETRIC-SYNTHESIS OF THE LACTONE MOIETY OF MEVINIC ACID
LAUTENS, M
MA, SH
YEE, A
TETRAHEDRON LETTERS, 1995, 36 (24) : 4185 - 4188
[32] ASYMMETRIC-SYNTHESIS OF BETA-CARBOXYASPARTIC ACID
WILLIAMS, RM
SINCLAIR, PJ
ZHAI, WX
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (02) : 482 - 483
[33] ASYMMETRIC-SYNTHESIS OF BETA-LACTAMS AND ITS APPLICATION TO AMINO-ACID AND PEPTIDE-SYNTHESIS
OJIMA, I
CHEN, HJC
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1986, 191 : 39 - ORGN
[34] ASYMMETRIC-SYNTHESIS OF (S)-4,5-DIFLUORO-2-METHYLINDOLINE
TSUJI, K
ISHIKAWA, H
SYNTHETIC COMMUNICATIONS, 1994, 24 (20) : 2943 - 2953
[35] ASYMMETRIC-SYNTHESIS OF 3-ALKOXYCARBONYL-2-AMINO-5-CYANO-4,6-DIPHENYL-4H-PYRANS
MARTIN, N
MARTINEZGRAU, A
SEOANE, C
MARCO, JL
ALBERT, A
CANO, FH
TETRAHEDRON-ASYMMETRY, 1994, 5 (08) : 1435 - 1438
[36] ASYMMETRIC-SYNTHESIS OF BOTH ENANTIOMERS OF 2-TRIFLUOROMETHYL-4-AMINOBUTYRIC ACID
YAMAZAKI, T
OHNOGI, T
KITAZUME, T
TETRAHEDRON-ASYMMETRY, 1990, 1 (04) : 215 - 218
[37] ASYMMETRIC-SYNTHESIS FROM ALPHA-AMINO-ACIDS - SOME REACTIONS OF (S)-PYROGLUTAMATE
WOO, KC
JONES, K
TETRAHEDRON LETTERS, 1991, 32 (47) : 6949 - 6952
[38] EPOXIDES, AMINO-ALCOHOLS, AND AZIRIDINES AS KEY INTERMEDIATES IN THE ASYMMETRIC-SYNTHESIS OF (S)-FENFLURAMINE
GOUMENT, B
DUHAMEL, L
MAUGE, R
BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE, 1993, 130 (04): : 459 - 466
[39] AN ASYMMETRIC-SYNTHESIS OF BICYCLIC LACTONES AND ITS APPLICATION TO THE ASYMMETRIC-SYNTHESIS OF (1R,3S)-CIS-CHRYSANTHEMIC ACID
MUKAIYAMA, T
YAMASHITA, H
ASAMI, M
CHEMISTRY LETTERS, 1983, (03) : 385 - 388
[40] ASYMMETRIC-SYNTHESIS OF (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID - THE UNKNOWN AMINO-ACID COMPONENT OF MICROGININ
BUNNAGE, ME
BURKE, AJ
DAVIES, SG
GOODWIN, CJ
TETRAHEDRON-ASYMMETRY, 1994, 5 (02) : 203 - 206

← 1 2 3 4 5 →