ASYMMETRIC-SYNTHESIS OF S-(+)-4-AMINO-5-HEXYNOIC ACID

被引：18
|
作者：
MCALONAN, H [1 ]
STEVENSON, PJ [1 ]
机构：
[1] QUEENS UNIV BELFAST,SCH CHEM,BELFAST BT9 5AG,ANTRIM,NORTH IRELAND
来源：
TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 01期
关键词：
D O I：
10.1016/0957-4166(94)00380-T
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
4-Amino-5-hexynoic acid is efficiently synthesised in eight steps (overall yield 10%) from commercially available (S)-glutamic acid. The key step was conversion of an aldehyde to an acetylene using diethylmethydiazophosphonate.
引用
收藏
页码：239 / 244
页数：6
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