FRIEDEL-CRAFTS APPROACH TO ELECTRON DEFICIENT CYCLIC ALPHA-AMINO-ACIDS

被引：16
|
作者：
KOTHA, S [1 ]
ANGLOS, D [1 ]
KUKI, A [1 ]
机构：
[1] CORNELL UNIV,BAKER LAB,DEPT CHEM,ITHACA,NY 14853
来源：
TETRAHEDRON LETTERS | 1992年 / 33卷 / 12期
基金：
美国国家卫生研究院;
关键词：
ELECTRON DEFICIENT ALPHA-AMINO ACID; FRIEDEL-CRAFTS ACYLATION;
D O I：
10.1016/S0040-4039(00)91676-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An electron deficient 2,2-dimethyl-1-H-phenalene-1,3-dione based cyclic alpha-amino acid was synthesized in 7 steps using Friedel-Crafts acylation as the key step. A new recipe was found to deprotect the required phthalimide protecting group in highly hindered substrates.
引用
收藏
页码：1569 / 1572
页数：4
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