A Tale of Absent Crystalline Lens in an Eye with Retinoblastoma

Purpose: To report the clinicopathological correlation of absent crystalline lens in an eye with retinoblastoma. Methods: A 1-year-old female child was brought to our patient services for pain and swelling in the right eye since the past few months. The child was diagnosed to have bilateral retinoblastoma and was suspected to have absence of crystalline lens in the right eye on the basis of clinical findings and ocular imaging. After 3 cycles of chemotherapy for suspected extraocular extension of tumor, she underwent enucleation. Absence of crystalline lens was confirmed on both gross and microscopic pathology. Results: We present a child with retinoblastoma, suspected to have absence of crystalline lens clinically and on ocular imaging (ultrasound and MRI), which was finally confirmed on ocular pathology examination post enucleation. Conclusion: We report for the first time clinicopathologically proven absence of crystalline lens in an eye with retinoblastoma. (c) 2018 S. Karger AG, Basel.