DENSE BODIES;
FILAMENTS;
LEIOMYOSARCOMA;
MYXOID STROMA;
MUSCLE SPECIFIC ACTIN;
D O I:
10.1111/j.1440-1827.1995.tb03410.x
中图分类号:
R36 [病理学];
学科分类号:
100104 ;
摘要:
A primary myxoid leiomyosarcoma arising from the peripheral bronchus of the right middle lobe was removed from a 20 year old man and examined by immunohistochemistry and electron microscopy. The tumor was well circumscribed, yellow-whitish focal polypoid growth into the bronchial lumen and consisted of spindle cells with abundant myxoid substance in the stroma. Intrapulmonary metastasis, invasion to the bronchial wall and a few mitotic figures were found. Immunohistochemically, several, but not all, tumor cells were positive against anti-vimentin, anti-S-100 protein, anti-myosin and anti-muscle specific actin, Ultrastructurally, tumor cells had thin filaments with dense bodies, pinocytic vesicles and discontinuous basal lamina. These findings indicate a myoxoid variant of leiomyosarcoma arising from mesenchyme in the peribronchial area.
机构:
HARVARD UNIV, MASSACHUSETTS GEN HOSP, SCH MED, JAMES HOMER WRIGHT PATHOL LABS, BOSTON, MA 02114 USAHARVARD UNIV, MASSACHUSETTS GEN HOSP, SCH MED, JAMES HOMER WRIGHT PATHOL LABS, BOSTON, MA 02114 USA
KING, ME
DICKERSIN, GR
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机构:
HARVARD UNIV, MASSACHUSETTS GEN HOSP, SCH MED, JAMES HOMER WRIGHT PATHOL LABS, BOSTON, MA 02114 USAHARVARD UNIV, MASSACHUSETTS GEN HOSP, SCH MED, JAMES HOMER WRIGHT PATHOL LABS, BOSTON, MA 02114 USA
DICKERSIN, GR
SCULLY, RE
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机构:
HARVARD UNIV, MASSACHUSETTS GEN HOSP, SCH MED, JAMES HOMER WRIGHT PATHOL LABS, BOSTON, MA 02114 USAHARVARD UNIV, MASSACHUSETTS GEN HOSP, SCH MED, JAMES HOMER WRIGHT PATHOL LABS, BOSTON, MA 02114 USA