THERAPEUTIC LYMPHADENECTOMY IN MELANOMAS OF THE HEAD AND NECK

被引:12
|
作者
VANDEVRIE, W
EGGERMONT, AMM
VANPUTTEN, WLJ
WIGGERS, T
机构
[1] DR DANIEL DEN HOED CANC CTR,DEPT SURG ONCOL,GROENE HILLEDIJK 301,3075 EA ROTTERDAM,NETHERLANDS
[2] DANIEL DENHOED CANC CTR,DEPT STAT,3075 EA ROTTERDAM,NETHERLANDS
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 1993年 / 15卷 / 05期
关键词
D O I
10.1002/hed.2880150503
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
This retrospective study describes patients with locoregionally metastasized melanoma of the head and neck. All patients underwent a therapeutic lymph node dissection. The 3-year survival rate was 35%. Duration of disease-free interval, number of lymph nodes involved, and extent of neck dissection proved of no influence on survival rates. Locoregional recurrence occurred in 10 patients and always proved to be a sign of systemic dissemination. Ultimately, 19 patients developed systemic disease. More than 40% developed cerebral metastases and the cerebrum was the second most involved site. As cerebral involvement occurs often in head and neck melanoma, a computed tomography or magnetic resonance imaging scan of the brain is recommended in the routine work-up before lymph node dissection. Furthermore, because the extent of the surgical procedure had no influence on local recurrence rate and overall survival, a selective approach, preserving functional structures, is advocated. (C) 1993 John Wiley & Sons, Inc.
引用
收藏
页码:377 / 381
页数:5
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