SYNTHESIS OF A POTENT AND SELECTIVE NONPEPTIDE CCK-B GASTRIN RECEPTOR ANTAGONIST TRITIATED LIGAND

被引：10

作者：

HILL, D ^{[1
]}

HORWELL, DC ^{[1
]}

HUNTER, JC ^{[1
]}

KNEEN, CO ^{[1
]}

PRITCHARD, MC ^{[1
]}

SUMANCHAUHAN, N ^{[1
]}

机构：

[1] PARKE DAVIS & CO,NEUROSCI RES CTR,ADDENBROOKES HOSP SITE,HILLS RD,CAMBRIDGE CB2 2QB,ENGLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 05期

关键词：

D O I：

10.1016/S0960-894X(00)80686-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The synthesis of a novel, potent and selective non-peptide gastrin/CCK-B receptor antagonist in a tritiated form is described, via a route which allows for introduction of the radiolabel in the final step.

引用

页码：885 / 888

页数：4

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