EFFECT OF SITE-SPECIFIC MODIFICATION ON RESTRICTION ENDONUCLEASES AND DNA MODIFICATION METHYLTRANSFERASES

被引：327
|
作者：
MCCLELLAND, M
NELSON, M
RASCHKE, E
机构：
[1] MEGABASE RES PROD, LINCOLN, NE 68503 USA
[2] UNIV BONN, D-53115 BONN, GERMANY
来源：
NUCLEIC ACIDS RESEARCH | 1994年 / 22卷 / 17期
关键词：
D O I：
10.1093/nar/22.17.3640
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Restriction endonucleases have site-specific interactions with DNA that can often be inhibited by site-specific DNA methylation and other site-specific DNA modifications. However, such inhibition cannot generally be predicted. The empirically acquired data on these effects are tabulated for over 320 restriction endonucleases. In addition, a table of known site-specific DNA modification methyltransferases and their specificities is presented along with EMBL database accession numbers for cloned genes.
引用
收藏
页码：3640 / 3659
页数：20
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