SYNTHESIS OF SUBSTITUTED 3-CYANO-2-PYRIDONES CATALYZED BY LIPASE FROM CANDIDA-CYLINDRACEA

被引：0
|
作者：
MIJIN, DZ
ANTONOVIC, DG
MISICVUKOVIC, MM
机构：
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1994年 / 33卷 / 03期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Lipase from Candida cylindracea has been used to synthesize the substituted 3-cyano-2-pyridones by cyclization of 1, 3-diketones with cyanoacetamide in water at 40-degrees-C. Synthesis has been performed in an excess of cyanoacetamide and the products have been analyzed by IR and H-1 NMR spectroscopy.
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页码：309 / 311
页数：3
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