SYNTHESIS OF SUBSTITUTED 3-CYANO-2-PYRIDONES CATALYZED BY LIPASE FROM CANDIDA-CYLINDRACEA

被引：0
|
作者：
MIJIN, DZ
ANTONOVIC, DG
MISICVUKOVIC, MM
机构：
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1994年 / 33卷 / 03期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Lipase from Candida cylindracea has been used to synthesize the substituted 3-cyano-2-pyridones by cyclization of 1, 3-diketones with cyanoacetamide in water at 40-degrees-C. Synthesis has been performed in an excess of cyanoacetamide and the products have been analyzed by IR and H-1 NMR spectroscopy.
引用
收藏
页码：309 / 311
页数：3
相关论文
共 50 条
  • [1] INTERESTERIFICATION AND SYNTHESIS BY CANDIDA-CYLINDRACEA LIPASE IN MICROEMULSIONS
    BELLO, M
    THOMAS, D
    LEGOY, MD
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 146 (01) : 361 - 367
  • [2] SYNTHESIS OF NOVEL FURYL-SUBSTITUTED 3-CYANO-2-PYRIDONES
    BALABAN, MC
    BALABAN, TS
    BOLOGA, U
    BALABAN, AT
    REVUE ROUMAINE DE CHIMIE, 1990, 35 (10-12) : 1005 - 1008
  • [3] SYNTHESIS OF ANNELATED 3-CYANO-2-PYRIDONES
    CHORVAT, RJ
    RADAK, SE
    TETRAHEDRON LETTERS, 1980, 21 (05) : 421 - 424
  • [4] THE ESTERASE PROFILE OF A LIPASE FROM CANDIDA-CYLINDRACEA
    BRAHIMIHORN, MC
    GUGLIELMINO, ML
    ELLING, L
    SPARROW, LG
    BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1042 (01) : 51 - 54
  • [5] Synthesis of substituted 3-cyano-2-pyridones: Part III - Enzyme kinetics
    Mijin, D
    Misic-Vukovic, MM
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1998, 37 (10): : 988 - 994
  • [6] Synthesis of substituted 3-cyano-2-pyridones: Part IV. Influence of 3-alkyl-2,4-pentanedione and N-alkyl cyanoacetamide structure on the enzyme catalyzed synthesis of substituted 3-cyano-2-pyridones
    Mijin, DZ
    Milic, BD
    Misic-Vukovic, MM
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2006, 45 (04): : 993 - 1003
  • [7] ENZYMATIC FAT SPLITTING WITH LIPASE FROM CANDIDA-CYLINDRACEA
    LINFIELD, W
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1982, 59 (04) : A266 - A266
  • [8] ORGN 133-Synthesis of 3-cyano-2-pyridones from malononitrile
    Kite, Camille M.
    Huehls, C. Bryan
    Sammelson, Robert E.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
  • [9] IMMOBILIZATION OF LIPASE FROM CANDIDA-CYLINDRACEA ON INORGANIC SUPPORTS
    MORENO, JM
    SINISTERRA, JV
    JOURNAL OF MOLECULAR CATALYSIS, 1994, 93 (03): : 357 - 369
  • [10] REGIOSELECTIVE AND CHEMOSELECTIVE PROPERTIES OF LIPASE FROM CANDIDA-CYLINDRACEA
    PEDROCCHIFANTONI, G
    SERVI, S
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1992, (08): : 1029 - 1033
12345