Coronary heart disease;
Risk factors;
Control determinants;
Primary care;
D O I:
10.1016/S0214-9168(10)70001-2
中图分类号:
R6 [外科学];
学科分类号:
1002 ;
100210 ;
摘要:
Introduction: The objective of secondary prevention of cardiovascular disease is to reduce the risk of a new cardiovascular event and increase survival. Patients in secondary prevention are at very high risk and represent the first priority in the prevention of cardiovascular disease. The aim of this study was to identify the determinants of poor control of risk factors in coronary patients attended in primary care. Methods: We performed a retrospective multicenter evaluation study with review of medical records and telephone calls to patients diagnosed with coronary heart disease attended in five primary care centers in the provinces of Barcelona and Gerona. Results: A total of 736 patients were studied, with a mean age of 72.11 years (71.4% were male). The following determinants of uncontrolled blood pressure (BP > 140/90 mmHg or BP > 130/80 mmHg in patients with diabetes mellitus or renal insufficiency) were identified: 1. Not being diagnosed with myocardial infarction (odds ratio [OR] = 1.61; 95% confidence interval [CI], 1.07-2.43); 2. Having a diagnosis of diabetes mellitus (OR = 4.26; 95% CI, 2.76-6.57): 3. Having a diagnosis of hypertension (OR = 2.67; 95% CI, 1.71-4.17), and 4. Not being diagnosed with chronic obstructive pulmonary disease (OR = 1.98; 95% CI, 1.01-3.89). The following determinants of poor lipid control (low-density lipoprotein cholesterol > 100 mg/dl) were identified: 1. Having a diagnosis of dyslipidemia (OR = 1.91; 95% CI, 1.21-3.03); 2. Not being diagnosed with hypertension (OR = 1.97; 95% CI, 1.23-3.14), and 3. Not being treated with statins or other lipid-lowering drugs (OR = 3.28; 95% CI, 1.78-6.06). Conclusions: Diabetes mellitus continues to be a major determinant of uncontrolled blood pressure and therefore antihypertensive therapy should be intensified in these patients. Lipid control could improve if new treatments were offered to patients not reaching therapeutic targets. (c) 2009 Elsevier Espana, S.L. and SEA. All rights reserved.
机构:
Univ Keele, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs, EnglandUniv Keele, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs, England
Dunn, Kate M.
Jordan, Kelvin P.
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Univ Keele, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs, EnglandUniv Keele, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs, England
Jordan, Kelvin P.
Croft, Peter R.
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Univ Keele, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs, EnglandUniv Keele, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs, England
机构:
Royal Victoria Hosp, Dept Rheumatol, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Dept Rheumatol, Belfast BT12 6BA, Antrim, North Ireland
Quinn, Anne
Finch, Michael B.
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Royal Victoria Hosp, Dept Rheumatol, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Dept Rheumatol, Belfast BT12 6BA, Antrim, North Ireland
Finch, Michael B.
Wright, Gary D.
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机构:
Royal Victoria Hosp, Dept Rheumatol, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Dept Rheumatol, Belfast BT12 6BA, Antrim, North Ireland
机构:
Univ Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, SerbiaUniv Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia
Projovic, Ivana
Vukadinovic, Dubravka
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Univ Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, SerbiaUniv Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia
Vukadinovic, Dubravka
Milovanovic, Olivera
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Univ Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, SerbiaUniv Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia
Milovanovic, Olivera
Jurisevic, Milena
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Univ Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, SerbiaUniv Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia
Jurisevic, Milena
Pavlovic, Radisa
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机构:
Univ Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, SerbiaUniv Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia
Pavlovic, Radisa
Jacovic, Sasa
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Univ Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, SerbiaUniv Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia
Jacovic, Sasa
Jankovic, Slobodan
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Univ Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia
Clin Ctr Kragujevac, Dept Clin Pharmacol, Kragujevac, SerbiaUniv Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia
Jankovic, Slobodan
Stefanovic, Srdjan
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Univ Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, SerbiaUniv Kragujevac, Dept Clin Pharm, Fac Med Sci, Kragujevac 34000, Serbia