Psychologists are required to perform professional services in accordance with American Psychological Association's (2010) Ethical Principles of Psychologists and Code of Conduct and policy regarding evidence-based practice. In light of these mandates, clinical competence includes the ability to take into consideration individual differences and client characteristics, context and preferences, including the contributions of religion and spirituality, in the practice of psychology. A review of the literature suggests that psychologists generally receive little education and training in the applied psychology of religion and spirituality, which calls into question the adequacy of their preparation. However, through the use of competency-based clinical supervision, competence can be enhanced through attention to the knowledge, skills, and attitudes that are assembled to conduct psychological treatment that is sensitive to the religious and spiritual beliefs, values, and commitments of patients.