MECHANISM OF INSECT RESISTANCE TO THE MICROBIAL INSECTICIDE BACILLUS-THURINGIENSIS

被引：315
|
作者：
VANRIE, J
MCGAUGHEY, WH
JOHNSON, DE
BARNETT, BD
VANMELLAERT, H
机构：
[1] STATE UNIV GHENT, AGROZOOL LAB, B-9000 GHENT, BELGIUM
[2] USDA ARS, N CENT REG, US GRAIN MKT RES LAB, MANHATTAN, KS 66502 USA
来源：
SCIENCE | 1990年 / 247卷 / 4938期
关键词：
D O I：
10.1126/science.2294593
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Receptor binding studies show that resistance of a laboratory-selected Plodia interpunctella strain to a Bacillus thuringiensis insecticidal crystal protein (ICP) is correlated with a 50-fold reduction in affinity of the membrane receptor for this protein. The strain is sensitive to a second type of ICP that apparently recognizes a different receptor. Understanding the mechanism of resistance will provide strategies to prevent or delay resistance and hence prolong the usefulness of B. thuringiensis ICPs as environmentally safe insecticides.
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页码：72 / 74
页数：3
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