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ACUTE TRYPTOPHAN DEPLETION AND INCREASED FOOD-INTAKE AND IRRITABILITY IN BULIMIA-NERVOSA
被引:0
|作者:
WELTZIN, TE
[1
]
FERNSTROM, MH
[1
]
FERNSTROM, JD
[1
]
NEUBERGER, SK
[1
]
KAYE, WH
[1
]
机构:
[1] UNIV PITTSBURGH,SCH MED,WESTERN PSYCHIAT INST & CLIN,DEPT PSYCHIAT,PITTSBURGH,PA
来源:
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D O I:
暂无
中图分类号:
R749 [精神病学];
学科分类号:
100205 ;
摘要:
Objective: Data suggest that serotonin activity is reduced in women at normal weight who have bulimia nervosa. The authors whether acute perturbations in serotonin activity could alter short-term eating behavior and mood. Method: They examined the effect of acute tryptophan depletion in 10 women with and 10 women without bulimia nervosa. Results: Women with bulimia nervosa exhibited an increase in caloric intake and mood irritability after acute tryptophan depletion. Conclusions: These results indicate that women with bulimia nervosa have an exaggerated or pathological response to transient alterations in serotonin activity.
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页码:1668 / 1671
页数:4
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